Standard name |
HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_DN |
Systematic name |
M2566 |
Brief description |
Genes distinguishing asparaginase resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples. |
Full description or abstract |
Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of patients is largely unknown. |
Collection |
C2: Curated CGP: Chemical and Genetic Perturbations |
Source publication |
Pubmed 15295046 Authors: Holleman A,Cheok MH,den Boer ML,Yang W,Veerman AJ,Kazemier KM,Pei D,Cheng C,Pui CH,Relling MV,Janka-Schaub GE,Pieters R,Evans WE |
Exact source |
Fig. 11S: R/S < 1 |
Related gene sets |
(show 15 additional gene sets from the source publication)
(show 28 gene sets from the same authors)
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External links |
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Filtered by similarity ?
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Source species |
Homo sapiens |
Contributed by |
Arthur Liberzon (MSigDB Team) |
Source platform or identifier namespace |
AFFY_HG_U133 |
Dataset references |
(show 1 datasets)
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Download gene set |
format: grp | gmt | xml | json | TSV metadata |
Compute overlaps ? |
(show collections to investigate for overlap with this gene set)
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Compendia expression profiles ? |
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Advanced query |
Further investigate
these 26 genes
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Gene families ? |
Categorize these
26 genes by gene family
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Show members |
(show 29 source identifiers mapped to 26 genes)
Source Id |
NCBI (Entrez) Gene Id |
Gene Symbol |
Gene Description |
200987_x_at |
10197 |
PSME3 |
proteasome activator subunit 3 [S... |
201140_s_at |
5878 |
RAB5C |
RAB5C, member RAS oncogene family... |
201376_s_at |
3185 |
HNRNPF |
heterogeneous nuclear ribonucleop... |
201668_x_at |
4082 |
MARCKS |
myristoylated alanine rich protei... |
201669_s_at |
4082 |
MARCKS |
myristoylated alanine rich protei... |
201670_s_at |
4082 |
MARCKS |
myristoylated alanine rich protei... |
202557_at |
6782 |
HSPA13 |
heat shock protein family A (Hsp7... |
202769_at |
901 |
CCNG2 |
cyclin G2 [Source:HGNC Symbol;Acc... |
203094_at |
9587 |
MAD2L1BP |
MAD2L1 binding protein [Source:HG... |
203274_at |
8263 |
F8A1 |
coagulation factor VIII associate... |
203311_s_at |
382 |
ARF6 |
ADP ribosylation factor 6 [Source... |
203388_at |
409 |
ARRB2 |
arrestin beta 2 [Source:HGNC Symb... |
203521_s_at |
24149 |
ZNF318 |
zinc finger protein 318 [Source:H... |
205644_s_at |
6637 |
SNRPG |
small nuclear ribonucleoprotein p... |
208656_s_at |
10983 |
CCNI |
cyclin I [Source:HGNC Symbol;Acc:... |
208739_x_at |
6613 |
SUMO2 |
small ubiquitin like modifier 2 [... |
211255_x_at |
9191 |
DEDD |
death effector domain containing ... |
211559_s_at |
901 |
CCNG2 |
cyclin G2 [Source:HGNC Symbol;Acc... |
212544_at |
9326 |
ZNHIT3 |
zinc finger HIT-type containing 3... |
212643_at |
93487 |
MAPK1IP1L |
mitogen-activated protein kinase ... |
212749_s_at |
25898 |
RCHY1 |
ring finger and CHY zinc finger d... |
216862_s_at |
100272147 |
CMC4 |
C-X9-C motif containing 4 [Source... |
217602_at |
5478 |
PPIA |
peptidylprolyl isomerase A [Sourc... |
217750_s_at |
65264 |
UBE2Z |
ubiquitin conjugating enzyme E2 Z... |
218027_at |
29088 |
MRPL15 |
mitochondrial ribosomal protein L... |
218333_at |
51009 |
DERL2 |
derlin 2 [Source:HGNC Symbol;Acc:... |
218438_s_at |
80306 |
MED28 |
mediator complex subunit 28 [Sour... |
218614_at |
55196 |
RESF1 |
retroelement silencing factor 1 [... |
218802_at |
55013 |
MCUB |
mitochondrial calcium uniporter d... |
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Version history |
3.1: First introduced
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A big thank you to everyone who responded to our request for emails of support for our grant application resubmission.
Reading them made us feel so appreciated and valued by all of you.
We hope we can continue to bring you GSEA/MSigDB in the years to come.
-The GSEA/MSigDB Team