Standard name |
HOLLEMAN_DAUNORUBICIN_B_ALL_UP |
Systematic name |
M2556 |
Brief description |
Genes distinguishing daunorubicin [PubChem=30323] resistant and sensitive B-lineage ALL; here - genes up-regulated in the drug resistant samples. |
Full description or abstract |
Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of patients is largely unknown. |
Collection |
C2: Curated CGP: Chemical and Genetic Perturbations |
Source publication |
Pubmed 15295046 Authors: Holleman A,Cheok MH,den Boer ML,Yang W,Veerman AJ,Kazemier KM,Pei D,Cheng C,Pui CH,Relling MV,Janka-Schaub GE,Pieters R,Evans WE |
Exact source |
Fig. 8S: R/S ratio > 1 |
Related gene sets |
(show 15 additional gene sets from the source publication)
(show 28 gene sets from the same authors)
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External links |
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Filtered by similarity ?
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Source species |
Homo sapiens |
Contributed by |
Arthur Liberzon (MSigDB Team) |
Source platform or identifier namespace |
AFFY_HG_U133 |
Dataset references |
(show 1 datasets)
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Download gene set |
format: grp | gmt | xml | json | TSV metadata |
Compute overlaps ? |
(show collections to investigate for overlap with this gene set)
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Compendia expression profiles ? |
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Advanced query |
Further investigate
these 10 genes
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Gene families ? |
Categorize these
10 genes by gene family
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Show members |
(show 10 source identifiers mapped to 10 genes)
Source Id |
NCBI (Entrez) Gene Id |
Gene Symbol |
Gene Description |
201184_s_at |
1108 |
CHD4 |
chromodomain helicase DNA binding protei... |
201694_s_at |
1958 |
EGR1 |
early growth response 1 [Source:HGNC Sym... |
203887_s_at |
7056 |
THBD |
thrombomodulin [Source:HGNC Symbol;Acc:H... |
204401_at |
3783 |
KCNN4 |
potassium calcium-activated channel subf... |
207452_s_at |
53942 |
CNTN5 |
contactin 5 [Source:HGNC Symbol;Acc:HGNC... |
209429_x_at |
8890 |
EIF2B4 |
eukaryotic translation initiation factor... |
209953_s_at |
11140 |
CDC37 |
cell division cycle 37, HSP90 cochaperon... |
210966_x_at |
23367 |
LARP1 |
La ribonucleoprotein 1, translational re... |
219737_s_at |
5101 |
PCDH9 |
protocadherin 9 [Source:HGNC Symbol;Acc:... |
220948_s_at |
476 |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha... |
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Version history |
3.1: First introduced
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