Standard name |
HOLLEMAN_VINCRISTINE_RESISTANCE_ALL_DN |
Systematic name |
M2562 |
Brief description |
Genes distinguishing vincristine [PubChem=5978] resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples. |
Full description or abstract |
Childhood acute lymphoblastic leukemia (ALL) is curable with chemotherapy in approximately 80 percent of patients. However, the cause of treatment failure in the remaining 20 percent of patients is largely unknown. |
Collection |
C2: Curated CGP: Chemical and Genetic Perturbations |
Source publication |
Pubmed 15295046 Authors: Holleman A,Cheok MH,den Boer ML,Yang W,Veerman AJ,Kazemier KM,Pei D,Cheng C,Pui CH,Relling MV,Janka-Schaub GE,Pieters R,Evans WE |
Exact source |
Fig. 10S: R/S ratio < 1 |
Related gene sets |
(show 15 additional gene sets from the source publication)
(show 28 gene sets from the same authors)
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External links |
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Filtered by similarity ?
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Source species |
Homo sapiens |
Contributed by |
Arthur Liberzon (MSigDB Team) |
Source platform or identifier namespace |
AFFY_HG_U133 |
Dataset references |
(show 1 datasets)
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Download gene set |
format: grp | gmt | xml | json | TSV metadata |
Compute overlaps ? |
(show collections to investigate for overlap with this gene set)
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Compendia expression profiles ? |
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Advanced query |
Further investigate
these 20 genes
|
Gene families ? |
Categorize these
20 genes by gene family
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Show members |
(show 24 source identifiers mapped to 20 genes)
Source Id |
NCBI (Entrez) Gene Id |
Gene Symbol |
Gene Description |
200061_s_at |
6229 |
RPS24 |
ribosomal protein S24 [Source:HGNC Symb... |
200088_x_at |
6136 |
RPL12 |
ribosomal protein L12 [Source:HGNC Symb... |
200593_s_at |
3192 |
HNRNPU |
heterogeneous nuclear ribonucleoprotein... |
200680_x_at |
3146 |
HMGB1 |
high mobility group box 1 [Source:HGNC ... |
200725_x_at |
6134 |
RPL10 |
ribosomal protein L10 [Source:HGNC Symb... |
200781_s_at |
6210 |
RPS15A |
ribosomal protein S15a [Source:HGNC Sym... |
200809_x_at |
6136 |
RPL12 |
ribosomal protein L12 [Source:HGNC Symb... |
200909_s_at |
6181 |
RPLP2 |
ribosomal protein lateral stalk subunit... |
200963_x_at |
6160 |
RPL31 |
ribosomal protein L31 [Source:HGNC Symb... |
201268_at |
4831 |
NME2 |
NME/NM23 nucleoside diphosphate kinase ... |
201426_s_at |
7431 |
VIM |
vimentin [Source:HGNC Symbol;Acc:HGNC:1... |
204490_s_at |
960 |
CD44 |
CD44 molecule (Indian blood group) [Sou... |
204559_s_at |
51690 |
LSM7 |
LSM7 homolog, U6 small nuclear RNA and ... |
208825_x_at |
6147 |
RPL23A |
ribosomal protein L23a [Source:HGNC Sym... |
208834_x_at |
6147 |
RPL23A |
ribosomal protein L23a [Source:HGNC Sym... |
212210_at |
26173 |
INTS1 |
integrator complex subunit 1 [Source:HG... |
212433_x_at |
6187 |
RPS2 |
ribosomal protein S2 [Source:HGNC Symbo... |
213084_x_at |
6147 |
RPL23A |
ribosomal protein L23a [Source:HGNC Sym... |
213377_x_at |
6206 |
RPS12 |
ribosomal protein S12 [Source:HGNC Symb... |
214271_x_at |
6136 |
RPL12 |
ribosomal protein L12 [Source:HGNC Symb... |
214369_s_at |
10235 |
RASGRP2 |
RAS guanyl releasing protein 2 [Source:... |
217733_s_at |
9168 |
TMSB10 |
thymosin beta 10 [Source:HGNC Symbol;Ac... |
218608_at |
23400 |
ATP13A2 |
ATPase cation transporting 13A2 [Source... |
218672_at |
79005 |
SCNM1 |
sodium channel modifier 1 [Source:HGNC ... |
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Version history |
3.1: First introduced
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