Human Gene Set: HP_ABNORMAL_CIRCULATING_GLOBULIN_CONCENTRATION


Standard name HP_ABNORMAL_CIRCULATING_GLOBULIN_CONCENTRATION
Systematic name M38530
Brief description Abnormal circulating globulin concentration
Full description or abstract An abnormal concentration of globulins in the blood. Albumin makes up more than half of the total protein present in serum. The remaining blood proteins except albumin and fibrinogen (which is not in serum) are referred to as globulins. The globulin fraction includes hundreds of serum proteins including carrier proteins, enzymes, complement, and immunoglobulins. Most of these are synthesized in the liver, although the immunoglobulins are synthesized by plasma cells. Globulins are divided into four groups by electrophoresis. The four fractions are alpha1, alpha2, beta and gamma, depending on their migratory pattern between the anode and the cathode. []
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0032179
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External links https://hpo.jax.org/app/browse/term/HP:0032179
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
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Version history 2023.1.Hs: Renamed from HP_ABNORMAL_CIRCULATING_GLOBULIN_LEVEL. Updated to HPO Release 2023-01-27.

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