Human Gene Set: HP_DECREASED_CD8_T_CELL_PROPORTION


Standard name HP_DECREASED_CD8_T_CELL_PROPORTION
Systematic name M36708
Brief description Decreased CD8+ T cell proportion
Full description or abstract Abnormal decrease of cytotoxic CD3+CD8+ T cells, measured as percentage of total CD3+ T cells in the blood, compared to a reference range for a given sex and age-group. These are usually measured within the TCR alpha/beta positive population. [https://orcid.org/0000-0002-0736-9199]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0005415
Related gene sets  
External links https://hpo.jax.org/app/browse/term/HP:0005415
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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Version history 2025.1.Hs: Renamed from HP_DECREASED_PROPORTION_OF_CD8_POSITIVE_T_CELLS. Updated to HPO Release 2025-05-06.

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