Human Gene Set: HP_DECREASED_NEUTROPHIL_OXIDATIVE_BURST


Standard name HP_DECREASED_NEUTROPHIL_OXIDATIVE_BURST
Systematic name M36219
Brief description Decreased neutrophil oxidative burst
Full description or abstract Abnormal decrease of neutrophil oxidative burst, commonly measured through oxidation of dihydrorhodamine (DHR) using flow cytometry or through nitroblue tetrazolium test (NBT) using optical microscopy, upon stimulation with phorbol-12-myristate-13-acetate (PMA), E. coli or other ligands. [https://orcid.org/0000-0002-0736-9199, PMID:27558335]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0003203
Related gene sets  
External links https://hpo.jax.org/app/browse/term/HP:0003203
Filtered by similarity ?
Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 9 genes
Gene families ? Categorize these 9 genes by gene family
Show members (show 9 source identifiers mapped to 9 genes)
Version history 2025.1.Hs: Renamed from HP_IMPAIRED_OXIDATIVE_BURST. Updated to HPO Release 2025-05-06.

See MSigDB license terms here. Please note that certain gene sets have special access terms.