Human Gene Set: HP_DIFFUSE_ALVEOLAR_HEMORRHAGE


Standard name HP_DIFFUSE_ALVEOLAR_HEMORRHAGE
Systematic name M38274
Brief description Diffuse alveolar hemorrhage
Full description or abstract A type of of pulmonary hemorrhage that originates from the pulmonary microcirculation, including the alveolar capillaries, arterioles, and venules. It presents with hemoptysis, anemia, diffuse lung infiltration, and acute respiratory failure. The diagnosis is confirmed by the observation of the accumulation of red blood cells, fibrin, or hemosiderin-laden macrophage in the alveolar space on pathologic biopsy. Hemosiderin, a product of hemoglobin degradation, appears at least 48-72 hours after bleeding and is helpful in distinguishing diffuse alveolar hemorrhage from surgical trauma. Mild interstitial thickening, organizing pneumonia, or diffuse alveolar damage can also be seen. [PMID:23678356]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0025420
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External links https://hpo.jax.org/app/browse/term/HP:0025420
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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Version history 2025.1.Hs: Updated to HPO Release 2025-05-06.

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