Human Gene Set: HP_FLOPPY_INFANT


Standard name HP_FLOPPY_INFANT
Systematic name M37312
Brief description Floppy infant
Full description or abstract Floppiness/hypotonia is defined as reduced resistance to passive movement of joints. Physical examination of floppy/hypotonic infants shows head lag, lack of shoulder and elbow muscle contraction on traction response, inability to tighten the shoulder girdle muscles (or slipping through) when held under the axillae, scarf sign (when the arm is pulled to the opposite side, the arm wraps around the neck with the elbow crossing midline), hyperdorsiflexion of the feet, easy apposition of the thumb against the forearm, feet touching the cheek with ease and without discomfort, frog leg position, and inverted U sign on ventral suspension (head, arms, and legs hanging down without elbow or knee flexion and the trunk rounded in a dome shape). [PMID:19078754]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0008947
Related gene sets  
External links https://hpo.jax.org/app/browse/term/HP:0008947
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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Version history 2025.1.Hs: Renamed from HP_INFANTILE_MUSCULAR_HYPOTONIA. Updated to HPO Release 2025-05-06.

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