Human Gene Set: HP_IMPAIRED_EXECUTIVE_FUNCTIONING


Standard name HP_IMPAIRED_EXECUTIVE_FUNCTIONING
Systematic name M47292
Brief description Impaired executive functioning
Full description or abstract A disturbance of executive functioning, which is broadly defined as the set of abilities that allow for the planning, executing, monitoring, and self-correcting of goal-directed behavior while inhibiting task-irrelevant behavior. At least some degree of executive skill is needed to complete most cognitive tasks, and deficits in executive abilities are central to many clinical conditions, including fronto-temporal dementia. [PMID:28631987]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0033051
Related gene sets  
External links https://hpo.jax.org/app/browse/term/HP:0033051
Filtered by similarity ?
Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 8 genes
Gene families ? Categorize these 8 genes by gene family
Show members (show 8 source identifiers mapped to 8 genes)
Version history 2023.2.Hs: First Introduced.

See MSigDB license terms here. Please note that certain gene sets have special access terms.