Human Gene Set: HP_INCREASED_CIRCULATING_LACTATE_CONCENTRATION


Standard name HP_INCREASED_CIRCULATING_LACTATE_CONCENTRATION
Systematic name M35671
Brief description Increased circulating lactate concentration
Full description or abstract Abnormally increased level of blood lactate (2-hydroxypropanoic acid). Lactate is produced from pyruvate by lactate dehydrogenase during normal metabolism. The terms lactate and lactic acid are often used interchangeably but lactate (the component measured in blood) is strictly a weak base whereas lactic acid is the corresponding acid. Lactic acidosis is often used clinically to describe elevated lactate but should be reserved for cases where there is a corresponding acidosis (pH below 7.35). [https://orcid.org/0000-0002-0736-9199, PMID:24079682]
Collection C5: Ontology
      HPO: Human Phenotype Ontology
Source publication  
Exact source HP:0002151
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External links https://hpo.jax.org/app/browse/term/HP:0002151
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Source species Homo sapiens
Contributed by Human Phenotype Ontology Group (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 Human_NCBI_Gene_ID
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Version history 2026.1.Hs: Updated to HPO Release 2026-01-08.


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