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Human Gene Set: KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM
Standard name
KEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM
Systematic name
M47811
Brief description
Pathway Definition from KEGG: B[a]P -- (CYP1A1,CYP1B1) >> EH >> AKR -> C22355 -> Semiquinone -> Superoxide
Full description or abstract
Benzo[a]pyrenre to CYP-mediated metabolism. Pathway ID: N01401. Pathway type: Env factor. Pathway class: nt06251 CYP-mediated ROS formation.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01401
Related gene sets
External links
https://www.kegg.jp/entry/N01401
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
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grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 11 genes
Gene families
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these 11 genes by gene family
Show members
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13 source identifiers mapped to 11 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
10327
10327
AKR1A1
aldo-keto reductase family 1 member A1 [Sour...
1109
1109
AKR1C4
aldo-keto reductase family 1 member C4 [Sour...
1543
1543
CYP1A1
cytochrome P450 family 1 subfamily A member ...
1545
1545
CYP1B1
cytochrome P450 family 1 subfamily B member ...
1645
1645
AKR1C1
aldo-keto reductase family 1 member C1 [Sour...
1646
1646
AKR1C2
aldo-keto reductase family 1 member C2 [Sour...
2052
2052
EPHX1
epoxide hydrolase 1 [Source:HGNC Symbol;Acc:...
2053
2053
EPHX2
epoxide hydrolase 2 [Source:HGNC Symbol;Acc:...
253152
253152
EPHX4
epoxide hydrolase 4 [Source:HGNC Symbol;Acc:...
79852
79852
EPHX3
epoxide hydrolase 3 [Source:HGNC Symbol;Acc:...
8644
8644
AKR1C3
aldo-keto reductase family 1 member C3 [Sour...
C00704
C05309
Version history
2023.2.Hs: First Introduced.
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