Human Gene Set: KEGG_MEDICUS_REFERENCE_INTEGRIN_ALPHAVBETA6_SIGNALING

Standard name

KEGG_MEDICUS_REFERENCE_INTEGRIN_ALPHAVBETA6_SIGNALING

Systematic name

M51282

Brief description

Pathway Definition from KEGG: (FN1,TN,DSP,LAP) -> ITGAV+ITGB6 -> (Adaptor,FAK,Src)

Full description or abstract

Integrin alphaVbeta6 signaling. Pathway ID: N01985. Pathway type: Reference. Pathway class: nt06548 Integrin signaling.

Collection

C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways

Source publication

Exact source

N01985

Related gene sets

External links

https://www.kegg.jp/entry/N01985

Filtered by similarity ?

Source species

Homo sapiens

Contributed by

Anthony Castanza (MSigDB Team)

Source platform or
identifier namespace

Human_NCBI_Gene_ID

Dataset references

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format: grp | gmt | xml | json | TSV metadata

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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)

Advanced query

Further investigate these 27 genes

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Show members

(show 27 source identifiers mapped to 27 genes)

Source Id	NCBI (Entrez) Gene Id	Gene Symbol	Gene Description
10979	10979	FERMT2	FERM domain containing kindlin 2 [Source:HGNC ...
1834	1834	DSPP	dentin sialophosphoprotein [Source:HGNC Symbol...
2316	2316	FLNA	filamin A [Source:HGNC Symbol;Acc:HGNC:3754]
2317	2317	FLNB	filamin B [Source:HGNC Symbol;Acc:HGNC:3755]
2335	2335	FN1	fibronectin 1 [Source:HGNC Symbol;Acc:HGNC:3778]
29780	29780	PARVB	parvin beta [Source:HGNC Symbol;Acc:HGNC:14653]
3371	3371	TNC	tenascin C [Source:HGNC Symbol;Acc:HGNC:5318]
3685	3685	ITGAV	integrin subunit alpha V [Source:HGNC Symbol;A...
3694	3694	ITGB6	integrin subunit beta 6 [Source:HGNC Symbol;Ac...
3987	3987	LIMS1	LIM zinc finger domain containing 1 [Source:HG...
55612	55612	FERMT1	FERM domain containing kindlin 1 [Source:HGNC ...
55679	55679	LIMS2	LIM zinc finger domain containing 2 [Source:HG...
55742	55742	PARVA	parvin alpha [Source:HGNC Symbol;Acc:HGNC:14652]
5747	5747	PTK2	protein tyrosine kinase 2 [Source:HGNC Symbol;...
5829	5829	PXN	paxillin [Source:HGNC Symbol;Acc:HGNC:9718]
63923	63923	TNN	tenascin N [Source:HGNC Symbol;Acc:HGNC:22942]
64098	64098	PARVG	parvin gamma [Source:HGNC Symbol;Acc:HGNC:14654]
6714	6714	SRC	SRC proto-oncogene, non-receptor tyrosine kina...
7040	7040	TGFB1	transforming growth factor beta 1 [Source:HGNC...
7094	7094	TLN1	talin 1 [Source:HGNC Symbol;Acc:HGNC:11845]
7143	7143	TNR	tenascin R [Source:HGNC Symbol;Acc:HGNC:11953]
7148	7148	TNXB	tenascin XB [Source:HGNC Symbol;Acc:HGNC:11976]
7414	7414	VCL	vinculin [Source:HGNC Symbol;Acc:HGNC:12665]
81	81	ACTN4	actinin alpha 4 [Source:HGNC Symbol;Acc:HGNC:166]
83660	83660	TLN2	talin 2 [Source:HGNC Symbol;Acc:HGNC:15447]
83706	83706	FERMT3	FERM domain containing kindlin 3 [Source:HGNC ...
87	87	ACTN1	actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]

Version history

2026.2.Hs: Updated to network file last modified on 2026-07-23

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The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology, and Regents of the University of California, subject to the terms and conditions of the Creative Commons Attribution 4.0 International License.

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