Human Gene Set: KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION
Standard name
KEGG_MEDICUS_VARIANT_MLL_ENL_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION
Systematic name
M47440
Brief description
Pathway Definition from KEGG: MLL-ENL => (MEIS1,HOXA9,HOXA10,HOXA11,SIX1,SIX4,EYA1,CDKN2C,HPGD,GRIA3,FUT8)
Full description or abstract
MLL-ENL fusion to transcriptional activation. Pathway ID: N00120. Pathway type: Variant. Pathway class: nt06240 Transcription (cancer).
Collection
C2: Curated CP: Canonical Pathways CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N00120
Related gene sets
External links
https://www.kegg.jp/entry/N00120
Filtered by similarity ?
Source species
Homo sapiens
Contributed by
Anthony Castanza (MSigDB Team)
Source platform or identifier namespace
Human_NCBI_Gene_ID
Dataset references
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
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these 13 genes
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13 genes by gene family
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(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
1031
1031
CDKN2C
cyclin dependent kinase inhibitor 2C [Source:H...
2138
2138
EYA1
EYA transcriptional coactivator and phosphatas...
2530
2530
FUT8
fucosyltransferase 8 [Source:HGNC Symbol;Acc:H...
2892
2892
GRIA3
glutamate ionotropic receptor AMPA type subuni...
3205
3205
HOXA9
homeobox A9 [Source:HGNC Symbol;Acc:HGNC:5109]
3206
3206
HOXA10
homeobox A10 [Source:HGNC Symbol;Acc:HGNC:5100]
3207
3207
HOXA11
homeobox A11 [Source:HGNC Symbol;Acc:HGNC:5101]
3248
3248
HPGD
15-hydroxyprostaglandin dehydrogenase [Source:...
4211
4211
MEIS1
Meis homeobox 1 [Source:HGNC Symbol;Acc:HGNC:7...
4297
4297
KMT2A
lysine methyltransferase 2A [Source:HGNC Symbo...
4298
4298
MLLT1
MLLT1 super elongation complex subunit [Source...
51804
51804
SIX4
SIX homeobox 4 [Source:HGNC Symbol;Acc:HGNC:10...
6495
6495
SIX1
SIX homeobox 1 [Source:HGNC Symbol;Acc:HGNC:10...
Version history
2026.2.Hs: Updated to network file last modified on 2026-07-23
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