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Human Gene Set: KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM
Standard name
KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_TRANSPORT_OF_CALCIUM
Systematic name
M47690
Brief description
Pathway Definition from KEGG: APP* -> Abeta -> NMDAR -> Ca2+ -- MCU -> Ca2+(mito) -- MPTP -> CYCS
Full description or abstract
Mutation-caused aberrant Abeta to transport of calcium. Pathway ID: N01003. Pathway type: Variant. Pathway class: nt06460 Alzheimer disease.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01003
Related gene sets
External links
https://www.kegg.jp/entry/N01003
Filtered by similarity
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Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
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grp
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TSV metadata
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H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
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GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 15 genes
Gene families
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these 15 genes by gene family
Show members
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15 source identifiers mapped to 15 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
2902
2902
GRIN1
glutamate ionotropic receptor NMDA type subu...
2903
2903
GRIN2A
glutamate ionotropic receptor NMDA type subu...
2904
2904
GRIN2B
glutamate ionotropic receptor NMDA type subu...
2905
2905
GRIN2C
glutamate ionotropic receptor NMDA type subu...
2906
2906
GRIN2D
glutamate ionotropic receptor NMDA type subu...
291
291
SLC25A4
solute carrier family 25 member 4 [Source:HG...
292
292
SLC25A5
solute carrier family 25 member 5 [Source:HG...
293
293
SLC25A6
solute carrier family 25 member 6 [Source:HG...
351
351
APP
amyloid beta precursor protein [Source:HGNC ...
54205
54205
CYCS
cytochrome c, somatic [Source:HGNC Symbol;Ac...
7416
7416
VDAC1
voltage dependent anion channel 1 [Source:HG...
7417
7417
VDAC2
voltage dependent anion channel 2 [Source:HG...
7419
7419
VDAC3
voltage dependent anion channel 3 [Source:HG...
83447
83447
SLC25A31
solute carrier family 25 member 31 [Source:H...
90550
90550
MCU
mitochondrial calcium uniporter [Source:HGNC...
Version history
2023.2.Hs: First Introduced.
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