login
register
GSEA Home
Downloads
Molecular Signatures Database
Documentation
Contact
Team
MSigDB Home
Human Collections
About
Browse
Search
Investigate
Gene Families
Mouse Collections
About
Browse
Search
Investigate
Help
Human Gene Set: KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY
Standard name
KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY
Systematic name
M47761
Brief description
Pathway Definition from KEGG: PRNP* -| VGCC(N,L-type) -> Ca2+
Full description or abstract
Scrapie conformation PrPSc to VGCC-Ca2+ -apoptotic pathway. Pathway ID: N01201. Pathway type: Variant. Pathway class: nt06465 Prion disease.
Collection
C2: Curated
CP: Canonical Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
Source publication
Exact source
N01201
Related gene sets
External links
https://www.kegg.jp/entry/N01201
Filtered by similarity
?
Source species
Homo sapiens
Contributed by
KEGG (Kyoto Encyclopedia of Genes and Genomes)
Source platform or
identifier namespace
Human_NCBI_Gene_ID
Dataset references
Download gene set
format:
grp
|
gmt
|
xml
|
json
|
TSV metadata
Compute overlaps
?
(
show
collections to investigate for overlap with this gene set)
H: Hallmark
C1: Positional
C2: Curated
CGP: Chemical and Genetic Perturbations
CP: Canonical Pathways
CP:BIOCARTA: BioCarta Pathways
CP:KEGG_MEDICUS: KEGG Medicus Pathways
CP:PID: PID Pathways
CP:REACTOME: Reactome Pathways
CP:WIKIPATHWAYS: WikiPathways
CP:KEGG_LEGACY: KEGG Legacy Pathways
C3: Regulatory Target
MIR: microRNA Targets
MIR:MIRDB: miRDB
MIR:MIR_LEGACY: MIR_Legacy
TFT: Transcription Factor Targets
TFT:GTRD: GTRD
TFT:TFT_LEGACY: TFT_Legacy
C4: Computational
3CA: Curated Cancer Cell Atlas gene sets
CGN: Cancer Gene Neighborhoods
CM: Cancer Modules
C5: Ontology
GO: Gene Ontology
GO:BP: GO Biological Process
GO:CC: GO Cellular Component
GO:MF: GO Molecular Function
HPO: Human Phenotype Ontology
C6: Oncogenic Signature
C7: Immunologic Signature
IMMUNESIGDB: ImmuneSigDB
VAX: HIPC Vaccine Response
C8: Cell Type Signature
Compendia expression profiles
?
NG-CHM interactive heatmaps
(
Please note that clustering takes a few seconds
)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Legacy heatmaps (PNG)
GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query
Further investigate
these 6 genes
Gene families
?
Categorize
these 6 genes by gene family
Show members
(
show
6 source identifiers mapped to 6 genes)
Source
Id
NCBI (Entrez)
Gene Id
Gene
Symbol
Gene
Description
5621
5621
PRNP
prion protein [Source:HGNC Symbol;Acc:HGNC:9449]
774
774
CACNA1B
calcium voltage-gated channel subunit alpha1 B ...
775
775
CACNA1C
calcium voltage-gated channel subunit alpha1 C ...
776
776
CACNA1D
calcium voltage-gated channel subunit alpha1 D ...
778
778
CACNA1F
calcium voltage-gated channel subunit alpha1 F ...
779
779
CACNA1S
calcium voltage-gated channel subunit alpha1 S ...
Version history
2023.2.Hs: First Introduced.
See
MSigDB license terms here
. Please note that certain gene sets have special access terms.