Human Gene Set: MTOR_UP.V1_DN

Standard name MTOR_UP.V1_DN
Systematic name M2670
Brief description Genes down-regulated by everolimus [PubChem=6442177] in prostate tissue.
Full description or abstract Wild-type littermates were treated with RAD001 or placebo and sacrificed at 12 and 48 h following the beginning of treatment.
Collection C6: Oncogenic Signature
Source publication Pubmed 15156201   Authors: Majumder PK,Febbo PG,Bikoff R,Berger R,Xue Q,McMahon LM,Manola J,Brugarolas J,McDonnell TJ,Golub TR,Loda M,Lane HA,Sellers WR
Exact source WT_PLACEBO vs WT_RAD001; bottom 200 genes (diff. of means)
Related gene sets (show 5 additional gene sets from the source publication)

(show 271 gene sets from the same authors)
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Source species Mus musculus
Contributed by Pablo Tamayo (Broad Institute)
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Dataset references (show 1 datasets)
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Compendia expression profiles ? GTEx compendium
Human tissue compendium (Novartis)
Global Cancer Map (Broad Institute)
NCI-60 cell lines (National Cancer Institute)
Advanced query Further investigate these 182 genes
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Show members (show 200 source identifiers mapped to 182 genes)
Version history 7.1: Fixed RIKEN identifiers.

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