Human Gene Set: RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP

For the Mouse gene set with the same name, see RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP

Standard name RAMPON_ENRICHED_LEARNING_ENVIRONMENT_LATE_UP
Systematic name M1651
Brief description Genes up-regulated in the brain cortex of mice that were exposed to an enriched learning environment for 2 or 14 days.
Full description or abstract An enriched environment is known to promote structural changes in the brain and to enhance learning and memory performance in rodents [Hebb, D. O. (1947) Am. Psychol. 2, 306-307]. To better understand the molecular mechanisms underlying these experience-dependent cognitive changes, we have used high-density oligonucleotide microarrays to analyze gene expression in the brain. Expression of a large number of genes changes in response to enrichment training, many of which can be linked to neuronal structure, synaptic plasticity, and transmission. A number of these genes may play important roles in modulating learning and memory capacity.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 11070096   Authors: Rampon C,Jiang CH,Dong H,Tang YP,Lockhart DJ,Schultz PG,Tsien JZ,Hu Y
Exact source Table 1: 3h and 6 hr > 0
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(show 73 gene sets from the same authors)
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Organism Mus musculus
Contributed by John Newman (University of Washington)
Source platform AFFY_Mu11K
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Version history 3.1: First introduced

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