Human Gene Set: SCHMAHL_PDGF_SIGNALING

For the Mouse gene set with the same name, see SCHMAHL_PDGF_SIGNALING

Standard name SCHMAHL_PDGF_SIGNALING
Systematic name M1285
Brief description These genes form a a network that controls specific processes downstream of PDGF signaling.
Full description or abstract Growth factor signaling leads to the induction or repression of immediate early genes, but how these genes act collectively as effectors of downstream processes remains unresolved. We have used gene trap-coupled microarray analysis to identify and mutate multiple platelet-derived growth factor (PDGF) intermediate early genes in mice. Mutations in these genes lead to a high frequency of phenotypes that affect the same cell types and processes as those controlled by the PDGF pathway. We conclude that these genes form a network that controls specific processes downstream of PDGF signaling.
Collection C2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 17143286   Authors: Schmahl J,Raymond CS,Soriano P
Exact source Table 1S
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Source species Mus musculus
Contributed by Leona Saunders (MSigDB Team)
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identifier namespace		 Mouse_RefSeq
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Version history 3.1: First introduced


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