Browse Human Gene Sets

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[about the MSigDB Human collections]

  • H (hallmark gene sets, 50 gene sets)
  • C1 (positional gene sets, 302 gene sets)
  • C2 (curated gene sets, 7411 gene sets)
    • CGP (chemical and genetic pertubations, 3494 gene sets)
    • CP (canonical pathways, 3917 gene sets)
  • C3 (regulatory gene sets, 3713 gene sets)
    • MIR (microRNA targets, 2598 gene sets)
    • TFT (all transcription factor targets, 1115 gene sets)
      • TFT:GTRD (GTRD transcription factor targets, 505 gene sets)
      • TFT:TFT_LEGACY (legacy transcription factor targets, 610 gene sets)
  • C4 (computational gene sets, 1006 gene sets)
    • 3CA (Curated Cancer Cell Atlas gene sets, 148 gene sets)
    • CGN (cancer gene neighborhoods, 427 gene sets)
    • CM (cancer modules, 431 gene sets)
  • C5 (ontology gene sets, 16107 gene sets)
    • GO (Gene Ontology, 10454 gene sets)
      • GO:BP (GO biological process, 7608 gene sets)
      • GO:CC (GO cellular component, 1026 gene sets)
      • GO:MF (GO molecular function, 1820 gene sets)
    • HPO (Human Phenotype Ontology, 5653 gene sets)
  • C6 (oncogenic gene sets, 189 gene sets)
  • C7 (immunologic gene sets, 5219 gene sets)
    • IMMUNESIGDB (ImmuneSigDB gene sets, 4872 gene sets)
    • VAX (vaccine response gene sets, 347 gene sets)
  • C8 (cell type signature gene sets, 840 gene sets)

Click on a gene set name to view its gene set page.

KEGG_ABC_TRANSPORTERS
KEGG_ACUTE_MYELOID_LEUKEMIA
KEGG_ADHERENS_JUNCTION
KEGG_ADIPOCYTOKINE_SIGNALING_PATHWA
Y

KEGG_ALANINE_ASPARTATE_AND_GLUTAMAT
E_METABOLISM

KEGG_ALDOSTERONE_REGULATED_SODIUM_R
EABSORPTION

KEGG_ALLOGRAFT_REJECTION
KEGG_ALPHA_LINOLENIC_ACID_METABOLIS
M

KEGG_ALZHEIMERS_DISEASE
KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUG
AR_METABOLISM

KEGG_AMINOACYL_TRNA_BIOSYNTHESIS
KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_
ALS

KEGG_ANTIGEN_PROCESSING_AND_PRESENT
ATION

KEGG_APOPTOSIS
KEGG_ARACHIDONIC_ACID_METABOLISM
KEGG_ARGININE_AND_PROLINE_METABOLIS
M

KEGG_ARRHYTHMOGENIC_RIGHT_VENTRICUL
AR_CARDIOMYOPATHY_ARVC

KEGG_ASCORBATE_AND_ALDARATE_METABOL
ISM

KEGG_ASTHMA
KEGG_AUTOIMMUNE_THYROID_DISEASE
KEGG_AXON_GUIDANCE
KEGG_B_CELL_RECEPTOR_SIGNALING_PATH
WAY

KEGG_BASAL_CELL_CARCINOMA
KEGG_BASAL_TRANSCRIPTION_FACTORS
KEGG_BASE_EXCISION_REPAIR
KEGG_BETA_ALANINE_METABOLISM
KEGG_BIOSYNTHESIS_OF_UNSATURATED_FA
TTY_ACIDS

KEGG_BLADDER_CANCER
KEGG_BUTANOATE_METABOLISM
KEGG_CALCIUM_SIGNALING_PATHWAY
KEGG_CARDIAC_MUSCLE_CONTRACTION
KEGG_CELL_ADHESION_MOLECULES_CAMS
KEGG_CELL_CYCLE
KEGG_CHEMOKINE_SIGNALING_PATHWAY
KEGG_CHRONIC_MYELOID_LEUKEMIA
KEGG_CIRCADIAN_RHYTHM_MAMMAL
KEGG_CITRATE_CYCLE_TCA_CYCLE
KEGG_COLORECTAL_CANCER
KEGG_COMPLEMENT_AND_COAGULATION_CAS
CADES

KEGG_CYSTEINE_AND_METHIONINE_METABO
LISM

KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INT
ERACTION

KEGG_CYTOSOLIC_DNA_SENSING_PATHWAY
KEGG_DILATED_CARDIOMYOPATHY
KEGG_DNA_REPLICATION
KEGG_DORSO_VENTRAL_AXIS_FORMATION
KEGG_DRUG_METABOLISM_CYTOCHROME_P45
0

KEGG_DRUG_METABOLISM_OTHER_ENZYMES
KEGG_ECM_RECEPTOR_INTERACTION
KEGG_ENDOCYTOSIS
KEGG_ENDOMETRIAL_CANCER
KEGG_EPITHELIAL_CELL_SIGNALING_IN_H
ELICOBACTER_PYLORI_INFECTION

KEGG_ERBB_SIGNALING_PATHWAY
KEGG_ETHER_LIPID_METABOLISM
KEGG_FATTY_ACID_METABOLISM
KEGG_FC_EPSILON_RI_SIGNALING_PATHWA
Y

KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOS
IS

KEGG_FOCAL_ADHESION
KEGG_FOLATE_BIOSYNTHESIS
KEGG_FRUCTOSE_AND_MANNOSE_METABOLIS
M

KEGG_GALACTOSE_METABOLISM
KEGG_GAP_JUNCTION
KEGG_GLIOMA
KEGG_GLUTATHIONE_METABOLISM
KEGG_GLYCEROLIPID_METABOLISM
KEGG_GLYCEROPHOSPHOLIPID_METABOLISM
KEGG_GLYCINE_SERINE_AND_THREONINE_M
ETABOLISM

KEGG_GLYCOLYSIS_GLUCONEOGENESIS
KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS
_CHONDROITIN_SULFATE

KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS
_HEPARAN_SULFATE

KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS
_KERATAN_SULFATE

KEGG_GLYCOSAMINOGLYCAN_DEGRADATION
KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS
_GANGLIO_SERIES

KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS
_GLOBO_SERIES

KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS
_LACTO_AND_NEOLACTO_SERIES

KEGG_GLYCOSYLPHOSPHATIDYLINOSITOL_G
PI_ANCHOR_BIOSYNTHESIS

KEGG_GLYOXYLATE_AND_DICARBOXYLATE_M
ETABOLISM

KEGG_GNRH_SIGNALING_PATHWAY
KEGG_GRAFT_VERSUS_HOST_DISEASE
KEGG_HEDGEHOG_SIGNALING_PATHWAY
KEGG_HEMATOPOIETIC_CELL_LINEAGE
KEGG_HISTIDINE_METABOLISM
KEGG_HOMOLOGOUS_RECOMBINATION
KEGG_HUNTINGTONS_DISEASE
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HC
M

KEGG_INOSITOL_PHOSPHATE_METABOLISM
KEGG_INSULIN_SIGNALING_PATHWAY
KEGG_INTESTINAL_IMMUNE_NETWORK_FOR_
IGA_PRODUCTION

KEGG_JAK_STAT_SIGNALING_PATHWAY
KEGG_LEISHMANIA_INFECTION
KEGG_LEUKOCYTE_TRANSENDOTHELIAL_MIG
RATION

KEGG_LIMONENE_AND_PINENE_DEGRADATIO
N

KEGG_LINOLEIC_ACID_METABOLISM
KEGG_LONG_TERM_DEPRESSION
KEGG_LONG_TERM_POTENTIATION
KEGG_LYSINE_DEGRADATION
KEGG_LYSOSOME
KEGG_MAPK_SIGNALING_PATHWAY
KEGG_MATURITY_ONSET_DIABETES_OF_THE
_YOUNG

KEGG_MELANOGENESIS
KEGG_MELANOMA
KEGG_METABOLISM_OF_XENOBIOTICS_BY_C
YTOCHROME_P450

KEGG_MISMATCH_REPAIR
KEGG_MTOR_SIGNALING_PATHWAY
KEGG_N_GLYCAN_BIOSYNTHESIS
KEGG_NATURAL_KILLER_CELL_MEDIATED_C
YTOTOXICITY

KEGG_NEUROACTIVE_LIGAND_RECEPTOR_IN
TERACTION

KEGG_NEUROTROPHIN_SIGNALING_PATHWAY
KEGG_NICOTINATE_AND_NICOTINAMIDE_ME
TABOLISM

KEGG_NITROGEN_METABOLISM
KEGG_NOD_LIKE_RECEPTOR_SIGNALING_PA
THWAY

KEGG_NON_HOMOLOGOUS_END_JOINING
KEGG_NON_SMALL_CELL_LUNG_CANCER
KEGG_NOTCH_SIGNALING_PATHWAY
KEGG_NUCLEOTIDE_EXCISION_REPAIR
KEGG_O_GLYCAN_BIOSYNTHESIS
KEGG_OLFACTORY_TRANSDUCTION
KEGG_ONE_CARBON_POOL_BY_FOLATE
KEGG_OOCYTE_MEIOSIS
KEGG_OTHER_GLYCAN_DEGRADATION
KEGG_OXIDATIVE_PHOSPHORYLATION
KEGG_P53_SIGNALING_PATHWAY
KEGG_PANCREATIC_CANCER
KEGG_PANTOTHENATE_AND_COA_BIOSYNTHE
SIS

KEGG_PARKINSONS_DISEASE
KEGG_PATHOGENIC_ESCHERICHIA_COLI_IN
FECTION

KEGG_PATHWAYS_IN_CANCER
KEGG_PENTOSE_AND_GLUCURONATE_INTERC
ONVERSIONS

KEGG_PENTOSE_PHOSPHATE_PATHWAY
KEGG_PEROXISOME
KEGG_PHENYLALANINE_METABOLISM
KEGG_PHOSPHATIDYLINOSITOL_SIGNALING
_SYSTEM

KEGG_PORPHYRIN_AND_CHLOROPHYLL_META
BOLISM

KEGG_PPAR_SIGNALING_PATHWAY
KEGG_PRIMARY_BILE_ACID_BIOSYNTHESIS
KEGG_PRIMARY_IMMUNODEFICIENCY
KEGG_PRION_DISEASES
KEGG_PROGESTERONE_MEDIATED_OOCYTE_M
ATURATION

KEGG_PROPANOATE_METABOLISM
KEGG_PROSTATE_CANCER
KEGG_PROTEASOME
KEGG_PROTEIN_EXPORT
KEGG_PROXIMAL_TUBULE_BICARBONATE_RE
CLAMATION

KEGG_PURINE_METABOLISM
KEGG_PYRIMIDINE_METABOLISM
KEGG_PYRUVATE_METABOLISM
KEGG_REGULATION_OF_ACTIN_CYTOSKELET
ON

KEGG_REGULATION_OF_AUTOPHAGY
KEGG_RENAL_CELL_CARCINOMA
KEGG_RENIN_ANGIOTENSIN_SYSTEM
KEGG_RETINOL_METABOLISM
KEGG_RIBOFLAVIN_METABOLISM
KEGG_RIBOSOME
KEGG_RIG_I_LIKE_RECEPTOR_SIGNALING_
PATHWAY

KEGG_RNA_DEGRADATION
KEGG_RNA_POLYMERASE
KEGG_SELENOAMINO_ACID_METABOLISM
KEGG_SMALL_CELL_LUNG_CANCER
KEGG_SNARE_INTERACTIONS_IN_VESICULA
R_TRANSPORT

KEGG_SPHINGOLIPID_METABOLISM
KEGG_SPLICEOSOME
KEGG_STARCH_AND_SUCROSE_METABOLISM
KEGG_STEROID_BIOSYNTHESIS
KEGG_STEROID_HORMONE_BIOSYNTHESIS
KEGG_SULFUR_METABOLISM
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS
KEGG_T_CELL_RECEPTOR_SIGNALING_PATH
WAY

KEGG_TASTE_TRANSDUCTION
KEGG_TAURINE_AND_HYPOTAURINE_METABO
LISM

KEGG_TERPENOID_BACKBONE_BIOSYNTHESI
S

KEGG_TGF_BETA_SIGNALING_PATHWAY
KEGG_THYROID_CANCER
KEGG_TIGHT_JUNCTION
KEGG_TOLL_LIKE_RECEPTOR_SIGNALING_P
ATHWAY

KEGG_TRYPTOPHAN_METABOLISM
KEGG_TYPE_I_DIABETES_MELLITUS
KEGG_TYPE_II_DIABETES_MELLITUS
KEGG_TYROSINE_METABOLISM
KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS
KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_
BIOSYNTHESIS

KEGG_VALINE_LEUCINE_AND_ISOLEUCINE_
DEGRADATION

KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRAC
TION

KEGG_VASOPRESSIN_REGULATED_WATER_RE
ABSORPTION

KEGG_VEGF_SIGNALING_PATHWAY
KEGG_VIBRIO_CHOLERAE_INFECTION
KEGG_VIRAL_MYOCARDITIS
KEGG_WNT_SIGNALING_PATHWAY