STANDARD_NAME GOBP_LEPTIN_MEDIATED_SIGNALING_PATHWAY SYSTEMATIC_NAME MM6799 COLLECTION M5:GO:BP MSIGDB_URL https://www.gsea-msigdb.org/gsea/msigdb/mouse/geneset/GOBP_LEPTIN_MEDIATED_SIGNALING_PATHWAY NAMESPACE Mouse_NCBI_Gene_ID DESCRIPTION_BRIEF The series of molecular signals initiated by leptin binding to its receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. [GOC:mah, GOC:signaling, GOC:yaf] DESCRIPTION_FULL PMID GEOID AUTHORS CONTRIBUTOR Gene Ontology CONTRIBUTOR_ORG Gene Ontology Consortium EXACT_SOURCE GO:0033210 FILTERED_BY_SIMILARITY EXTERNAL_NAMES_FOR_SIMILAR_TERMS EXTERNAL_DETAILS_URL http://amigo.geneontology.org/amigo/term/GO:0033210 SOURCE_MEMBERS 102774,15468,16846,16847,17751,20848,22234,59030,67378,72674,93759 GENE_SYMBOLS Bbs4,Prmt2,Lep,Lepr,Mt3,Stat3,Ugcg,Mkks,Bbs2,Adipor1,Sirt1 FOUNDER_NAMES