Mouse Gene Set: BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_DN
For the Human gene set with the same name, see BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_DN
Standard name
BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_DN
Systematic name
MM1337
Brief description
Tha authors analyzed RNA sequencing data to investigate the comprehensive transcriptomic landscape of Verteporfin treated Type 1 endometrial cancer cell lines, including HEC-1-A and HEC-1-B.
Full description or abstract
Verteporfin is a porphyrinic photosensitizer clinically used for the photodynamic treatment of age-related macular degeneration. The authors previously tested the efficacy of Verteporfin in endometrial cancer cells and observed cytotoxic and anti-proliferative effects.
Collection
M2: Curated CGP: Chemical and Genetic Perturbations
Source publication
Pubmed 30846786 Authors: Bang LG,Dasari VR,Kim D,Gogoi RP
Exact source
Table 2. Top 20 downregulated genes in HEC-1-A and HEC-1-B cells after VP treatment.
Related gene sets
(show 1 additional gene sets from the source publication)
External links
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405995/
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Source species
Homo sapiens
Contributed by
Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or identifier namespace
HUMAN_GENE_SYMBOL
Dataset references
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Advanced query
Further investigate
these 15 genes
Show members
(show 20 source identifiers mapped to 15 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
AOC3
11754
Aoc3
amine oxidase, copper containing 3 ...
BRICD5
319259
Bricd5
BRICHOS domain containing 5 [Source...
C9orf131
67317
Spata31g1
SPATA31 subfamily G member 1 [Sourc...
CEND1
57754
Cend1
cell cycle exit and neuronal differ...
DNLZ
52838
Dnlz
DNL-type zinc finger [Source:MGI Sy...
EFCAB12
212516
Efcab12
EF-hand calcium binding domain 12 [...
FTCD
14317
Ftcd
formiminotransferase cyclodeaminase...
HSPA6
IL9RP3
KLKP1
MIR4521
MMP25
240047
Mmp25
matrix metallopeptidase 25 [Source:...
MROH2A
100040766
Mroh2a
maestro heat-like repeat family mem...
MSLNL
328783
Mslnl
mesothelin-like [Source:MGI Symbol;...
PDE1B
18574
Pde1b
phosphodiesterase 1B, Ca2+-calmodul...
PPP1R27
68701
Ppp1r27
protein phosphatase 1, regulatory s...
RBFOX3
52897
Rbfox3
RNA binding protein, fox-1 homolog ...
RN7SL472P
SLC5A10
109342
Slc5a10
solute carrier family 5 (sodium/glu...
SRPK3
56504
Srpk3
serine/arginine-rich protein specif...
Version history
2022.1.Mm: First Introduced.
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