Mouse Gene Set: BIOCARTA_STEM_PATHWAY
                
               
            
          
    For the Human gene set with the same name, see BIOCARTA_STEM_PATHWAY  
  
  
    Standard name 
    BIOCARTA_STEM_PATHWAY 
   
  
    Systematic name 
    MM1471 
   
  
    Brief description 
    Regulation of hematopoiesis by cytokines 
   
  
    Full description or abstract 
    The process of hematopoesis is regulated by various cytokines. The combination of cytokines stimulates the proliferation and/or differentiation of the various hematopoietic cell types. Bone marrow stromal cells are the major source of hematopoietic cytokines in the non-infecteous state. In the presence of infection, cytokines produced by activated macrophages and TH cells induce hematopoietic activity. The induction by cytokines results in rapid expansion of the population of white blood cells to fight infection. The specific cytokines that affect a step of cell differentiation are placed adjacent to the arrow representing that step. Lines with '?' indicate likely, but still hypothetical pathways. 
   
  
    Collection 
    M2: Curated 
   
  
    Source publication 
      
   
  
    Exact source 
      
   
  
    Related gene sets 
    
      
         
        
      
     
   
  
    External links 
    https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_stemPathway.gif  
  
    Filtered by similarity ?  
    
    
        
     
   
  
    Source species 
    Mus musculus 
   
  
    Contributed by 
    BioCarta 
   
  
    Source platform or 
    MOUSE_SEQ_ACCESSION 
   
  
    Dataset references 
    
       
      
      
      
     
   
  
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        Mouse Transcriptomic BodyMap compendium 
       
      
        Mouse Transcriptomic BodyMap compendium 
       
      
     
   
  
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        these 14 genes
      
     
   
  
  
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        (show  14 source identifiers mapped to 14 genes)
       
      
        
        
          
            Source 
            NCBI (Entrez) 
            Gene 
            Gene 
           
          
            
              NM_001113530 
              12977 Csf1 colony stimulating factor 1 (macrophage) ... 
             
          
            
              NM_007942 
              13856 Epo erythropoietin [Source:MGI Symbol;Acc:MGI... 
             
          
            
              NM_008350 
              16156 Il11 interleukin 11 [Source:MGI Symbol;Acc:MGI... 
             
          
            
              NM_008366 
              16183 Il2 interleukin 2 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_008371 
              16196 Il7 interleukin 7 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_008373 
              16198 Il9 interleukin 9 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_009857 
              12525 Cd8a CD8 subunit alpha [Source:MGI Symbol;Acc:... 
             
          
            
              NM_009969 
              12981 Csf2 colony stimulating factor 2 (granulocyte-... 
             
          
            
              NM_009971 
              12985 Csf3 colony stimulating factor 3 (granulocyte)... 
             
          
            
              NM_010556 
              16187 Il3 interleukin 3 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_010558 
              16191 Il5 interleukin 5 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_013488 
              12504 Cd4 CD4 antigen [Source:MGI Symbol;Acc:MGI:88... 
             
          
            
              NM_021283 
              16189 Il4 interleukin 4 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_031168 
              16193 Il6 interleukin 6 [Source:MGI Symbol;Acc:MGI:... 
             
          
        
       
     
   
  
    Version history 
    
      
        
        2022.1.Mm: First Introduced.
        
      
            
      
     
   
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