Mouse Gene Set: BIOCARTA_STEM_PATHWAY
                
               
            
          
  
 
 
 
 
  
    For the Human gene set with the same name, see BIOCARTA_STEM_PATHWAY  
  
  
    Standard name 
    BIOCARTA_STEM_PATHWAY 
   
  
    Systematic name 
    MM1471 
   
  
    Brief description 
    Regulation of hematopoiesis by cytokines 
   
  
    Full description or abstract 
    The process of hematopoesis is regulated by various cytokines. The combination of cytokines stimulates the proliferation and/or differentiation of the various hematopoietic cell types. Bone marrow stromal cells are the major source of hematopoietic cytokines in the non-infecteous state. In the presence of infection, cytokines produced by activated macrophages and TH cells induce hematopoietic activity. The induction by cytokines results in rapid expansion of the population of white blood cells to fight infection. The specific cytokines that affect a step of cell differentiation are placed adjacent to the arrow representing that step. Lines with '?' indicate likely, but still hypothetical pathways. 
   
  
    Collection 
    M2: Curated       CP: Canonical Pathways             CP:BIOCARTA: BioCarta Pathways 
   
  
    Source publication 
      
   
  
    Exact source 
      
   
  
    Related gene sets 
    
      
         
        
      
     
   
  
    External links 
    https://data.broadinstitute.org/gsea-msigdb/msigdb/biocarta/mouse/m_stemPathway.gif  
   
  
    Filtered by similarity ?  
       
    
    
        
     
   
  
    Source species 
    Mus musculus 
   
  
    Contributed by 
    BioCarta 
   
  
    Source platform or identifier namespace 
    MOUSE_SEQ_ACCESSION 
   
  
    Dataset references 
    
       
      
      
      
     
   
  
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        (show  14 source identifiers mapped to 14 genes)
       
       
      
        
        
          
            Source Id 
            NCBI (Entrez) Gene Id 
            Gene Symbol 
            Gene Description 
           
          
            
              NM_001113530 
              12977  
              Csf1  
              colony stimulating factor 1 (macrophage) ... 
             
          
            
              NM_007942 
              13856  
              Epo  
              erythropoietin [Source:MGI Symbol;Acc:MGI... 
             
          
            
              NM_008350 
              16156  
              Il11  
              interleukin 11 [Source:MGI Symbol;Acc:MGI... 
             
          
            
              NM_008366 
              16183  
              Il2  
              interleukin 2 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_008371 
              16196  
              Il7  
              interleukin 7 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_008373 
              16198  
              Il9  
              interleukin 9 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_009857 
              12525  
              Cd8a  
              CD8 subunit alpha [Source:MGI Symbol;Acc:... 
             
          
            
              NM_009969 
              12981  
              Csf2  
              colony stimulating factor 2 (granulocyte-... 
             
          
            
              NM_009971 
              12985  
              Csf3  
              colony stimulating factor 3 (granulocyte)... 
             
          
            
              NM_010556 
              16187  
              Il3  
              interleukin 3 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_010558 
              16191  
              Il5  
              interleukin 5 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_013488 
              12504  
              Cd4  
              CD4 antigen [Source:MGI Symbol;Acc:MGI:88... 
             
          
            
              NM_021283 
              16189  
              Il4  
              interleukin 4 [Source:MGI Symbol;Acc:MGI:... 
             
          
            
              NM_031168 
              16193  
              Il6  
              interleukin 6 [Source:MGI Symbol;Acc:MGI:... 
             
          
        
       
     
   
  
    Version history 
    
      
        
        2022.1.Mm: First Introduced.
        
      
            
      
     
   
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