Mouse Gene Set: DURAND_STROMA_NS_UP

For the Human gene set with the same name, see DURAND_STROMA_NS_UP

Standard name DURAND_STROMA_NS_UP
Systematic name MM962
Brief description Genes up-regulated in the HSC non-supportive stromal cell lines.
Full description or abstract Stromal cell lines represent an exceptional tool to study the role on the microenvironment on hematopoietic stem cell (HSC) activity. We have compared the expression profile of HSC supportive vs non-supportive stromal lines generated from different hematopoietic tissues in the mouse, i.e the aorta-gonad-mesonephros (AGM) region, the fetal liver and the adult bone marrow, sequentially activated during development. In this study, six stromal lines were used with one HSC supportive and one non-supportive for each tissue (triplicate samples for each stromal line). We used Mouse Gene 1.0 ST microrrays in combination with GSEA and statistical analysis to identify lists of genes that segregate HSC supportive from non-supportive stromal lines.
Collection M2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication  
Exact source personal communication
Related gene sets  
External links
Filtered by similarity ?
Source species Mus musculus
Contributed by Charles Durand (Pierre and Marie Curie University)
Source platform or
identifier namespace
Mouse_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 172 genes
Show members (show 172 source identifiers mapped to 172 genes)
Version history 2022.1.Mm: First Introduced.

See MSigDB license terms here. Please note that certain gene sets have special access terms.