Mouse Gene Set: GOBP_BLOOD_COAGULATION_INTRINSIC_PATHWAY

For the Human gene set with the same name, see GOBP_BLOOD_COAGULATION_INTRINSIC_PATHWAY

Standard name GOBP_BLOOD_COAGULATION_INTRINSIC_PATHWAY
Systematic name MM5107
Brief description A protein activation cascade that initiates blood coagulation, triggered when Factor XII, prekallikrein (PK) and high-molecular-weight kininogen (HK) assemble on a suitable surface or polymer. This results in the reciprocal activation of factor XII to Factor XIIa by kallikrein, and PK to kallikrein by Factor XIIa. The resulting generation of Factor XIIa activates Factor XI to Factor XIa, which then converts Factor IX to Factor IXa. Factor IXa converts Factor X to Xa. Factor Xa then initiates the common pathway. [GOC:add, GOC:mah, GOC:pde, PMID:26018600]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0007597
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0007597
Filtered by similarity ?
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Mm: Updated to GO Release 2025-10-10.


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