An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining). [GOC:rph, PMID:18584027]
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Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
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