Mouse Gene Set: GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY

For the Human gene set with the same name, see GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY

Standard name GOBP_G_PROTEIN_COUPLED_RECEPTOR_SIGNALING_PATHWAY
Systematic name MM5009
Brief description The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0007186
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0007186
Filtered by similarity ?
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Mouse_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 1965 genes
Show members (show 1973 source identifiers mapped to 1965 genes)
Version history  

See MSigDB license terms here. Please note that certain gene sets have special access terms.