Mouse Gene Set: GOBP_MARGINAL_ZONE_B_CELL_DIFFERENTIATION

For the Human gene set with the same name, see GOBP_MARGINAL_ZONE_B_CELL_DIFFERENTIATION

Standard name GOBP_MARGINAL_ZONE_B_CELL_DIFFERENTIATION
Systematic name MM4232
Brief description The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL). [GOC:jal, ISBN:0781735149]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0002315
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0002315
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Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Mm: Updated to GO Release 2025-10-10.


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