Mouse Gene Set: GOBP_MDA_5_SIGNALING_PATHWAY

For the Human gene set with the same name, see GOBP_MDA_5_SIGNALING_PATHWAY

Standard name GOBP_MDA_5_SIGNALING_PATHWAY
Systematic name MM7328
Brief description The series of molecular signals initiated by the binding of dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1). MDA-5 detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. [GOC:bf, PMID:19620789, PMID:33087405]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0039530
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0039530
Filtered by similarity ?
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Mm: Updated to GO Release 2025-10-10.


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