Mouse Gene Set: GOBP_PIRNA_MEDIATED_GENE_SILENCING_BY_MRNA_DESTABILIZATION


Standard name GOBP_PIRNA_MEDIATED_GENE_SILENCING_BY_MRNA_DESTABILIZATION
Systematic name MM17959
Brief description A cytoplasmic post-transcriptional gene silencing pathway in which piRNAs direct the cleavage of target mRNAs. The target mRNA, often transcribed from a transposable element, is destabilized by the activity of a PIWI class endonuclease within the piRNA-induced silencing complex. This may also be accompanied by mRNA deadenylation and decapping. [PMID:29281264, PMID:33419460]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0140991
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0140991
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Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
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Version history 2025.1.Mm: Updated to GO Release 2025-03-16.

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