Mouse Gene Set: GOBP_TRANSCRIPTION_PAUSING_BY_RNA_POLYMERASE_II

For the Human gene set with the same name, see GOBP_TRANSCRIPTION_PAUSING_BY_RNA_POLYMERASE_II

Standard name GOBP_TRANSCRIPTION_PAUSING_BY_RNA_POLYMERASE_II
Systematic name MM20068
Brief description A transcription halt following transcription initiation but prior to elongation, during which RNA polymerase II pauses approximately 20-60 nucleotides downstream of the transcriptional start site before proceeding into productive elongation. Transcription pausing starts following phosphorylation of the C-terminal domain (CTD) of RNA polymerase II subunit POLR2A at Ser-5 and stops following phosphorylation of POLR2A by the P-TEFb complex. [PMID:33271312, PMID:35816930]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:BP: GO Biological Process
Source publication  
Exact source GO:0160239
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0160239
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Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace		 Mouse_NCBI_Gene_ID
Dataset references  
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Version history 2026.1.Mm: Updated to GO Release 2025-10-10.


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