Mouse Gene Set: GOBP_TYPE_2_MITOPHAGY
For the Human gene set with the same name, see GOBP_TYPE_2_MITOPHAGY
Standard name
GOBP_TYPE_2_MITOPHAGY
Systematic name
MM9410
Brief description
The selective autophagy process in which a mitochondrion is degraded by macroautophagy in a process initiated by mitochondrial depolarization (mtDepo) followed by Parkin binding, and ubiquitination of outer membrane proteins, to remove potentially harm-inducing dysfunctional/damaged mitochondria. [GOC:vw, PMID:25009776, PMID:25349190]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:BP: GO Biological Process
Source publication
Exact source
GO:0061734
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0061734
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 17 genes
Show members
(show 17 source identifiers mapped to 17 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
11983
11983
Atp5if1
ATP synthase inhibitory factor subunit 1 [S...
12539
12539
Cdc37
cell division cycle 37 [Source:MGI Symbol;A...
14466
14466
Gba1
glucosylceramidase beta 1 [Source:MGI Symbo...
15185
15185
Hdac6
histone deacetylase 6 [Source:MGI Symbol;Ac...
15277
15277
Hk2
hexokinase 2 [Source:MGI Symbol;Acc:MGI:131...
170731
170731
Mfn2
mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442...
22333
22333
Vdac1
voltage-dependent anion channel 1 [Source:M...
320528
320528
Vps13c
vacuolar protein sorting 13C [Source:MGI Sy...
50873
50873
Prkn
parkin RBR E3 ubiquitin protein ligase [Sou...
53600
53600
Timm23
translocase of inner mitochondrial membrane...
59026
59026
Huwe1
HECT, UBA and WWE domain containing 1 [Sour...
64704
64704
Htra2
HtrA serine peptidase 2 [Source:MGI Symbol;...
66169
66169
Tomm7
translocase of outer mitochondrial membrane...
68350
68350
Mul1
mitochondrial ubiquitin ligase activator of...
68943
68943
Pink1
PTEN induced putative kinase 1 [Source:MGI ...
71648
71648
Optn
optineurin [Source:MGI Symbol;Acc:MGI:1918898]
75788
75788
Smurf1
SMAD specific E3 ubiquitin protein ligase 1...
Version history
2025.1.Mm: Renamed from GOBP_PARKIN_MEDIATED_STIMULATION_OF_MITOPHAGY_IN_RESPONSE_TO_MITOCHONDRIAL_DEPOLARIZATION. Updated to GO Release 2025-03-16.
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