Mouse Gene Set: GOCC_CYTOLYTIC_GRANULE
                
               
            
          
    For the Human gene set with the same name, see GOCC_CYTOLYTIC_GRANULE  
  
  
    Standard name 
    GOCC_CYTOLYTIC_GRANULE 
   
  
    Systematic name 
    MM12336 
   
  
    Brief description 
    A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells. [GOC:jl, PMID:11052265, PMID:12766758] 
   
  
    Full description or abstract 
      
   
  
    Collection 
    M5: Ontology 
   
  
    Source publication 
      
   
  
    Exact source 
    GO:0044194 
   
  
    Related gene sets 
    
      
         
        
      
     
   
  
    External links 
    http://amigo.geneontology.org/amigo/term/GO:0044194  
  
    Filtered by similarity ?  
    
    
        
     
   
  
    Source species 
    Mus musculus 
   
  
    Contributed by 
    Gene Ontology (Gene Ontology Consortium) 
   
  
    Source platform or 
    Mouse_NCBI_Gene_ID 
   
  
    Dataset references 
    
       
      
      
      
     
   
  
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    format: grp  | gmt  | xml  | json  | TSV metadata  
   
  
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    Compendia expression profiles ?  
    
    
      
      
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        Mouse Transcriptomic BodyMap compendium 
       
      
        Mouse Transcriptomic BodyMap compendium 
       
      
     
   
  
    Advanced query 
    
      
      Further investigate  
        these 18 genes
      
     
   
  
  
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        (show  18 source identifiers mapped to 18 genes)
       
      
        
        
          
            Source 
            NCBI (Entrez) 
            Gene 
            Gene 
           
          
            
              12317 
              12317 Calr calreticulin [Source:MGI Symbol;Acc:MGI:8... 
             
          
            
              14939 
              14939 Gzmb granzyme B [Source:MGI Symbol;Acc:MGI:109... 
             
          
            
              14940 
              14940 Gzmc granzyme C [Source:MGI Symbol;Acc:MGI:109... 
             
          
            
              14941 
              14941 Gzmd granzyme D [Source:MGI Symbol;Acc:MGI:109... 
             
          
            
              14942 
              14942 Gzme granzyme E [Source:MGI Symbol;Acc:MGI:109... 
             
          
            
              14943 
              14943 Gzmf granzyme F [Source:MGI Symbol;Acc:MGI:109... 
             
          
            
              14944 
              14944 Gzmg granzyme G [Source:MGI Symbol;Acc:MGI:109... 
             
          
            
              16573 
              16573 Kif5b kinesin family member 5B [Source:MGI Symb... 
             
          
            
              16783 
              16783 Lamp1 lysosomal-associated membrane protein 1 [... 
             
          
            
              18646 
              18646 Prf1 perforin 1 (pore forming protein) [Source... 
             
          
            
              19073 
              19073 Srgn serglycin [Source:MGI Symbol;Acc:MGI:97756] 
             
          
            
              20911 
              20911 Stxbp2 syntaxin binding protein 2 [Source:MGI Sy... 
             
          
            
              21843 
              21843 Tial1 Tia1 cytotoxic granule-associated RNA bin... 
             
          
            
              245839 
              245839 Gzmn granzyme N [Source:MGI Symbol;Acc:MGI:267... 
             
          
            
              66222 
              66222 Serpinb1a serine (or cysteine) peptidase inhibitor,... 
             
          
            
              67166 
              67166 Arl8b ADP-ribosylation factor-like 8B [Source:M... 
             
          
            
              72310 
              72310 Nkg7 natural killer cell group 7 sequence [Sou... 
             
          
            
              75234 
              75234 Rnf19b ring finger protein 19B [Source:MGI Symbo... 
             
          
        
       
     
   
  
    Version history 
    
      
        
        2025.1.Mm: Updated to GO Release 2025-03-16.
        
      
            
      
     
   
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