Mouse Gene Set: GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX

For the Human gene set with the same name, see GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX

Standard name GOCC_DNA_DEPENDENT_PROTEIN_KINASE_DNA_LIGASE_4_COMPLEX
Systematic name MM17427
Brief description A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV. [GOC:jl, GOC:mah, PMID:10854421, PMID:12235392, PMID:17072889]
Full description or abstract  
Collection M5: Ontology
      GO: Gene Ontology
            GO:CC: GO Cellular Component
Source publication  
Exact source GO:0005958
Related gene sets  
External links http://amigo.geneontology.org/amigo/term/GO:0005958
Filtered by similarity ?
Source species Mus musculus
Contributed by Gene Ontology (Gene Ontology Consortium)
Source platform or
identifier namespace
Mouse_NCBI_Gene_ID
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 6 genes
Show members (show 6 source identifiers mapped to 6 genes)
Version history 2026.1.Mm: Updated to GO Release 2025-10-10.


Creative Commons Attribution 4.0 International License (CC-BY-4.0)

The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology, and Regents of the University of California, subject to the terms and conditions of the Creative Commons Attribution 4.0 International License.

See the full MSigDB license terms here.