Mouse Gene Set: GOCC_ESC_E_Z_COMPLEX
For the Human gene set with the same name, see GOCC_ESC_E_Z_COMPLEX
Standard name
GOCC_ESC_E_Z_COMPLEX
Systematic name
MM12245
Brief description
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. [GOC:bf, GOC:krc, GOC:sp, PMID:12408863, PMID:12408864, PMID:17107999, PMID:20064375, PMID:31123059, PMID:33232890]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:CC: GO Cellular Component
Source publication
Exact source
GO:0035098
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0035098
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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format: grp | gmt | xml | json | TSV metadata
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Advanced query
Further investigate
these 18 genes
Show members
(show 18 source identifiers mapped to 18 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
103551
103551
Epop
elongin BC and polycomb repress...
105246908
105246908
Chaer1
cardiac hypertrophy associated ...
11569
11569
Aebp2
AE binding protein 2 [Source:MG...
13626
13626
Eed
embryonic ectoderm development ...
14055
14055
Ezh1
enhancer of zeste 1 polycomb re...
14056
14056
Ezh2
enhancer of zeste 2 polycomb re...
15182
15182
Hdac2
histone deacetylase 2 [Source:M...
16468
16468
Jarid2
jumonji and AT-rich interaction...
17765
17765
Mtf2
metal response element binding ...
19646
19646
Rbbp4
retinoblastoma binding protein ...
21652
21652
Phf1
PHD finger protein 1 [Source:MG...
245688
245688
Rbbp7
retinoblastoma binding protein ...
319903
319903
9630013A20Rik
RIKEN cDNA 9630013A20 gene [Sou...
52615
52615
Suz12
SUZ12 polycomb repressive compl...
54427
54427
Dnmt3l
DNA methyltransferase 3-like [S...
68729
68729
Trim37
tripartite motif-containing 37 ...
74016
74016
Phf19
PHD finger protein 19 [Source:M...
93759
93759
Sirt1
sirtuin 1 [Source:MGI Symbol;Ac...
Version history
2025.1.Mm: Updated to GO Release 2025-03-16.
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