Mouse Gene Set: GOMF_PORE_FORMING_ACTIVITY
For the Human gene set with the same name, see GOMF_PORE_FORMING_ACTIVITY
Standard name
GOMF_PORE_FORMING_ACTIVITY
Systematic name
MM16590
Brief description
An activity in which a protein is inserted into the membrane of another cell where it forms transmembrane pores. Pores disrupts the integrity of the cell membrane, resulting in deregulated ion homeostasis, cellular dysfunction, and can result in cell death. [PMID:1406491, PMID:25157079, PMID:34387717]
Full description or abstract
Collection
M5: Ontology GO: Gene Ontology GO:MF: GO Molecular Function
Source publication
Exact source
GO:0140911
Related gene sets
External links
http://amigo.geneontology.org/amigo/term/GO:0140911
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Gene Ontology (Gene Ontology Consortium)
Source platform or identifier namespace
Mouse_NCBI_Gene_ID
Dataset references
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Advanced query
Further investigate
these 29 genes
Show members
(show 44 source identifiers mapped to 29 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
100038927
100038927
Defa30
defensin, alpha, 30 [Source:MGI Symb...
100041688
100041688
Defa35
defensin, alpha, 35 [Source:MGI Symb...
100041759
100041759
Defa41
defensin, alpha, 41 [Source:MGI Symb...
100041787
100041787
Defa40
defensin, alpha, 40 [Source:MGI Symb...
100041811
100041811
Defa27
defensin, alpha, 27 [Source:MGI Symb...
100041895
100041895
Defa37
defensin, alpha, 37 [Source:MGI Symb...
100041952
100041952
Defa34
defensin, alpha, 34 [Source:MGI Symb...
100294660
100294660
Defa2
defensin, alpha, 2 [Source:MGI Symbo...
100503970
100503970
AY761185
cDNA sequence AY761185 [Source:MGI S...
13216
13218
13218
Defa29
defensin, alpha, 29 [Source:MGI Symb...
13219
13221
13222
13226
13226
Defa31
defensin, alpha, 31 [Source:MGI Symb...
13229
13230
13232
13233
13234
13235
13236
13236
Defa25
defensin, alpha, 25 [Source:MGI Symb...
13237
13237
Defa3
defensin, alpha, 3 [Source:MGI Symbo...
13238
13239
13239
Defa5
defensin, alpha, 5 [Source:MGI Symbo...
13240
13241
13242
13243
17476
17476
Mpeg1
macrophage expressed gene 1 [Source:...
18646
18646
Prf1
perforin 1 (pore forming protein) [S...
23855
23855
Defa17
defensin, alpha, 17 [Source:MGI Symb...
382000
382000
Defa39
defensin, alpha, 39 [Source:MGI Symb...
382059
382059
Defa22
defensin, alpha, 22 [Source:MGI Symb...
497114
497114
Defa23
defensin, alpha, 23 [Source:MGI Symb...
503491
503491
Defa24
defensin, alpha, 24 [Source:MGI Symb...
626682
626682
Defa28
defensin, alpha, 28 [Source:MGI Symb...
626708
626708
Defa26
defensin, alpha, 26 [Source:MGI Symb...
634825
634825
Defa38
defensin, alpha, 38 [Source:MGI Symb...
66298
66298
Defa21
defensin, alpha, 21 [Source:MGI Symb...
665927
665927
Defa42
defensin, alpha, 42 [Source:MGI Symb...
67468
67468
Mmd
monocyte to macrophage differentiati...
68009
68009
Defa20
defensin, alpha, 20 [Source:MGI Symb...
75104
75104
Mmd2
monocyte to macrophage differentiati...
Version history
2026.1.Mm: Updated to GO Release 2025-10-10.
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The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .