| Standard name | JARDIM_PERASSI_TRIPLE_NEGATIVE_BREAST_CANCER_MOUSE_XENOGRAFT_MELATONIN_DN | 
  
    | Systematic name | MM453 | 
  
    | Brief description | Gene sets differentially expressed in mouse cells, characterized by the tumor microenvironment between melatonin-treated and control samples in a xenograft model of triple-negative breast cancer using Balb/c athymic nude mice. | 
  
    | Full description or abstract | Balb/c athymic nude mice are unable to produce T-cells and are, therefore, immunodeficient. They are characterized by abnormal hair growth and defective development of the thymic epithelium. Insufficient information was provided in the publication regarding which specific Balb/c athymic nude mouse strain was used to generate the data. | 
  
    | Collection | M2: Curated CGP: Chemical and Genetic Perturbations
 | 
  
    | Source publication | Pubmed 30700756   Authors: Jardim-Perassi BV,Alexandre PA,Sonehara NM,de Paula-Junior R,Reis Júnior O,Fukumasu H,Chammas R,Coutinho LL,Zuccari DAPC | 
  
    | Exact source | Supplementary Table 2. Differentially expressed genes in the mouse cells, characterized by the tumor microenvironment between melatonin-treated and control samples. | 
  
    | Related gene sets | (show 1 additional gene sets from the source publication) 
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    | External links | https://www.ncbi.nlm.nih.gov/pubmed/30700756 
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    | Filtered by similarity ? |  | 
  
    | Source species | Mus musculus | 
  
    | Contributed by | Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX)) | 
  
    | Source platform or identifier namespace
 | Mouse_NCBI_Gene_ID | 
  
    | Dataset references |  | 
  
    | Download gene set | format: grp | gmt | xml | json | TSV metadata | 
  
    | Compute overlaps ? | (show collections to investigate for overlap with this gene set) 
 | 
  
    | Compendia expression profiles ? | NG-CHM interactive heatmaps (Please note that clustering takes a few seconds)
 Mouse Transcriptomic BodyMap compendium
 
 Legacy heatmaps (PNG)
 Mouse Transcriptomic BodyMap compendium
 | 
  
    | Advanced query | Further investigate 
        these 14 genes | 
  
  
    | Show members | (show 14 source identifiers mapped to 14 genes) 
 
        
        
          
            | Source Id
 | NCBI (Entrez) Gene Id
 | Gene Symbol
 | Gene Description
 |  
              | 12830 | 12830 | Col4a5 | collagen, type IV, alpha 5 [Source:MGI Symb... |  
              | 13511 | 13511 | Dsg2 | desmoglein 2 [Source:MGI Symbol;Acc:MGI:119... |  
              | 14049 | 14049 | Eya2 | EYA transcriptional coactivator and phospha... |  
              | 14063 | 14063 | F2rl1 | F2R like trypsin receptor 1 [Source:MGI Sym... |  
              | 14362 | 14362 | Fzd1 | frizzled class receptor 1 [Source:MGI Symbo... |  
              | 14735 | 14735 | Gpc4 | glypican 4 [Source:MGI Symbol;Acc:MGI:104902] |  
              | 18619 | 18619 | Penk | preproenkephalin [Source:MGI Symbol;Acc:MGI... |  
              | 18750 | 18750 | Prkca | protein kinase C, alpha [Source:MGI Symbol;... |  
              | 212728 | 212728 | Tarbp1 | TAR RNA binding protein 1 [Source:MGI Symbo... |  
              | 23964 | 23964 | Tenm2 | teneurin transmembrane protein 2 [Source:MG... |  
              | 244416 | 244416 | Ppp1r3b | protein phosphatase 1, regulatory subunit 3... |  
              | 263406 | 263406 | Plekhg3 | pleckstrin homology domain containing, fami... |  
              | 320878 | 320878 | Mical2 | microtubule associated monooxygenase, calpo... |  
              | 58998 | 58998 | Nectin3 | nectin cell adhesion molecule 3 [Source:MGI... |  | 
  
    | Version history | 2022.1.Mm: First Introduced. |