Mouse Gene Set: MP_ABNORMAL_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION
Standard name
MP_ABNORMAL_CARDIAC_EPITHELIAL_TO_MESENCHYMAL_TRANSITION
Systematic name
MM24598
Brief description
anomaly in the process by which endocardial cells of the atrioventricular canal or the outflow tract lose their epithelial characteristics, delaminate from the endocardial sheet, become migratory and invade the cardiac jelly, and develop mesenchymal characteristics eventually forming both the endocardial cushions required for septum and atrioventricular valve formation and the cushions of the outflow tract that form the conotruncal septum
Full description or abstract
Collection
M5: Ontology MPO: Mammalian Phenotype Ontology MPO:MP: Mammalian Phenotype
Source publication
Exact source
MP:0008825
Related gene sets
External links
https://www.informatics.jax.org/vocab/mp_ontology/MP:0008825
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or identifier namespace
MGI_ID
Dataset references
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Further investigate
these 18 genes
Show members
(show 18 source identifiers mapped to 18 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
MGI:103236
13636
Efna1
ephrin A1 [Source:MGI Symbol;Acc:MGI:10...
MGI:105082
107513
Ssr1
signal sequence receptor, alpha [Source...
MGI:107495
17898
Myl7
myosin, light polypeptide 7, regulatory...
MGI:107821
15117
Has2
hyaluronan synthase 2 [Source:MGI Symbo...
MGI:1096393
20583
Snai2
snail family zinc finger 2 [Source:MGI ...
MGI:1334444
22762
Zfpm2
zinc finger protein, multitype 2 [Sourc...
MGI:1336883
17130
Smad6
SMAD family member 6 [Source:MGI Symbol...
MGI:1341884
15214
Hey2
hairy/enhancer-of-split related with YR...
MGI:1923076
75826
Senp2
SUMO/sentrin specific peptidase 2 [Sour...
MGI:2153207
140484
Pofut1
protein O-fucosyltransferase 1 [Source:...
MGI:88574
13058
Cybb
cytochrome b-245, beta polypeptide [Sou...
MGI:95411
13867
Erbb3
erb-b2 receptor tyrosine kinase 3 [Sour...
MGI:96086
15242
Hhex
hematopoietically expressed homeobox [S...
MGI:97357
18109
Mycn
v-myc avian myelocytomatosis viral rela...
MGI:97363
18128
Notch1
notch 1 [Source:MGI Symbol;Acc:MGI:97363]
MGI:98369
20680
Sox7
SRY (sex determining region Y)-box 7 [S...
MGI:99511
19247
Ptpn11
protein tyrosine phosphatase, non-recep...
MGI:99612
13837
Epha3
Eph receptor A3 [Source:MGI Symbol;Acc:...
Version history
Creative Commons Attribution 4.0 International License (CC-BY-4.0)
The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .