Mouse Gene Set: MP_ABNORMAL_CIRCUMVENTRICULAR_ORGAN_MORPHOLOGY


Standard name MP_ABNORMAL_CIRCUMVENTRICULAR_ORGAN_MORPHOLOGY
Systematic name MM26407
Brief description any structural abnormality of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow; CVOs contain neural tissue and are an integral part of neuroendocrine function; all of the CVOs, besides the subcommissural organ, contain extensive vasculature and fenestrated capillaries which leads to a leaky BBB at the site of the organs; the lack of a BBB allows CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances
Full description or abstract  
Collection M5: Ontology
      MPO: Mammalian Phenotype Ontology
            MPO:MP: Mammalian Phenotype
Source publication  
Exact source MP:0013562
Related gene sets  
External links https://www.informatics.jax.org/vocab/mp_ontology/MP:0013562
Filtered by similarity ? (show 1 similar ontology term(s) from the external resource)
Source species Mus musculus
Contributed by Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 MGI_ID
Dataset references  
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