Mouse Gene Set: MP_ABNORMAL_INTESTINE_GOBLET_CELL_MORPHOLOGY


Standard name MP_ABNORMAL_INTESTINE_GOBLET_CELL_MORPHOLOGY
Systematic name MM22552
Brief description any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the small and large intestine, whose primary function is to secrete gel-forming mucins, the major components of mucus; the goblet cell is a highly polarized unicellular exocrine gland with the nucleus and other organelles concentrated at the base of the cell; the remainder of the cell's cytoplasm is occupied by membrane-bound secretory granules containing mucin; the goblet shape is due to the mucus laden granules in the apical part expanding, causing that part of the cell to balloon; the apical plasma membrane projects microvilli to give an increased surface area for secretion
Full description or abstract  
Collection M5: Ontology
      MPO: Mammalian Phenotype Ontology
            MPO:MP: Mammalian Phenotype
Source publication  
Exact source MP:0003449
Related gene sets  
External links https://www.informatics.jax.org/vocab/mp_ontology/MP:0003449
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Source species Mus musculus
Contributed by Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 MGI_ID
Dataset references  
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