Mouse Gene Set: MP_ABNORMAL_MAMMARY_GLAND_EPITHELIUM_PHYSIOLOGY


Standard name MP_ABNORMAL_MAMMARY_GLAND_EPITHELIUM_PHYSIOLOGY
Systematic name MM25284
Brief description any functional anomaly of the mammary gland epithelium which is normally enveloped by a basement membrane, embedded into fatty connective tissue stroma, and organized as a bilayer, with an inner luminal layer of secretory epithelial cells, and an outer basal layer; each cell layer expresses specific molecular markers; luminal epithelial cells are characterized by the expression of the receptors for systemic hormones, i.e. estrogens, progesterone and prolactin, whereas basal cells (aka myoepithelial cells) express smooth muscle contractile proteins; in functionally differentiated mammary gland, during lactation, luminal cells produce milk, whereas myoepithelial cells are contractile and serve for milk expulsion
Full description or abstract  
Collection M5: Ontology
      MPO: Mammalian Phenotype Ontology
            MPO:MP: Mammalian Phenotype
Source publication  
Exact source MP:0010172
Related gene sets  
External links https://www.informatics.jax.org/vocab/mp_ontology/MP:0010172
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Source species Mus musculus
Contributed by Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 MGI_ID
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