Mouse Gene Set: MP_GLOMERULAR_CRESCENT


Standard name MP_GLOMERULAR_CRESCENT
Systematic name MM25890
Brief description formation of a crescent-shaped (semi-lunar) glomerular lesion corresponding to extracapillary proliferation of Bowman's capsular epithelium and acquiring a fibroblast-like spindled morphology, possibly stimulated by release of fibrinogen from a ruptured glomerular basement membrane; epithelial crescents occur in aggressive forms of glomerulonephritis, may be accompanied by collagen and fibrin deposition and/or monocyte and macrophage proliferation, may protrude into Bowman's space, and ultimately compress and destroy the glomerular tuft
Full description or abstract  
Collection M5: Ontology
      MPO: Mammalian Phenotype Ontology
            MPO:MP: Mammalian Phenotype
Source publication  
Exact source MP:0011506
Related gene sets  
External links https://www.informatics.jax.org/vocab/mp_ontology/MP:0011506
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Source species Mus musculus
Contributed by Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or
identifier namespace
MGI_ID
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