Mouse Gene Set: MP_INCREASED_SUSCEPTIBILITY_TO_DOPAMINERGIC_NEURON_NEUROTOXICITY
Standard name
MP_INCREASED_SUSCEPTIBILITY_TO_DOPAMINERGIC_NEURON_NEUROTOXICITY
Systematic name
MM25859
Brief description
greater than normal amount of dopaminergic neuronal cell death following exposure to a neurotoxic compound, such as MPTP-induced cell death occurring through interference in mitochondrial metabolism
Full description or abstract
Collection
M5: Ontology MPO: Mammalian Phenotype Ontology MPO:MP: Mammalian Phenotype
Source publication
Exact source
MP:0011451
Related gene sets
External links
https://www.informatics.jax.org/vocab/mp_ontology/MP:0011451
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or identifier namespace
MGI_ID
Dataset references
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Advanced query
Further investigate
these 13 genes
Show members
(show 13 source identifiers mapped to 13 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
MGI:105094
11516
Adcyap1
adenylate cyclase activating polypepti...
MGI:106677
214084
Slc18a2
solute carrier family 18 (vesicular mo...
MGI:109354
22228
Ucp2
uncoupling protein 2 (mitochondrial, p...
MGI:1097153
20312
Cx3cl1
C-X3-C motif chemokine ligand 1 [Sourc...
MGI:1333815
13051
Cx3cr1
C-X3-C motif chemokine receptor 1 [Sou...
MGI:1333817
20519
Slc22a3
solute carrier family 22 (organic cati...
MGI:1929601
65113
Ndfip1
Nedd4 family interacting protein 1 [So...
MGI:2135637
57320
Park7
Parkinson disease (autosomal recessive...
MGI:3619401
723864
Mir425
microRNA 425 [Source:MGI Symbol;Acc:MG...
MGI:94924
13489
Drd2
dopamine receptor D2 [Source:MGI Symbo...
MGI:95832
14824
Grn
granulin [Source:MGI Symbol;Acc:MGI:95...
MGI:96559
16193
Il6
interleukin 6 [Source:MGI Symbol;Acc:M...
MGI:97384
18212
Ntrk2
neurotrophic tyrosine kinase, receptor...
Version history
Creative Commons Attribution 4.0 International License (CC-BY-4.0)
The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .