Mouse Gene Set: MP_RETINA_GANGLION_CELL_DEGENERATION
Standard name
MP_RETINA_GANGLION_CELL_DEGENERATION
Systematic name
MM24140
Brief description
degeneration or loss of ganglion neurons located in the innermost nuclear layer of the retina of that receive visual information from photoreceptors via various intermediate cells such as bipolar cells, amacrine cells, and horizontal cells; axons from these cells form the optic nerve and connect mainly to the lateral geniculate nucleus (LGN) and to the suprachiasmatic nucleus in the brain
Full description or abstract
Collection
M5: Ontology MPO: Mammalian Phenotype Ontology MPO:MP: Mammalian Phenotype
Source publication
Exact source
MP:0008067
Related gene sets
External links
https://www.informatics.jax.org/vocab/mp_ontology/MP:0008067
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or identifier namespace
MGI_ID
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 18 genes
Show members
(show 20 source identifiers mapped to 18 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
MGI:102524
18997
Pou4f2
POU domain, class 4, transcription fa...
MGI:1278315
16973
Lrp5
low density lipoprotein receptor-rela...
MGI:1298204
19063
Ppt1
palmitoyl-protein thioesterase 1 [Sou...
MGI:1349419
26926
Aifm1
apoptosis-inducing factor, mitochondr...
MGI:1859635
54630
Prickle3
prickle planar cell polarity protein ...
MGI:1891468
107515
Lgr4
leucine-rich repeat-containing G prot...
MGI:1916703
69453
Prss56
serine protease 56 [Source:MGI Symbol...
MGI:1918898
71648
Optn
optineurin [Source:MGI Symbol;Acc:MGI...
MGI:1921393
74143
Opa1
OPA1, mitochondrial dynamin like GTPa...
MGI:1921569
74319
Mettl23
methyltransferase like 23 [Source:MGI...
MGI:1933163
80890
Trim2
tripartite motif-containing 2 [Source...
MGI:2159339
171209
Asic3
acid-sensing ion channel 3 [Source:MG...
MGI:2442062
268396
Sh3pxd2b
SH3 and PX domains 2B [Source:MGI Sym...
MGI:6810184
MGI:88138
12043
Bcl2
B cell leukemia/lymphoma 2 [Source:MG...
MGI:95832
14824
Grn
granulin [Source:MGI Symbol;Acc:MGI:9...
MGI:97385
18213
Ntrk3
neurotrophic tyrosine kinase, recepto...
MGI:97531
18596
Pdgfrb
platelet derived growth factor recept...
MGI:98952
MGI:99255
14103
Fasl
Fas ligand [Source:MGI Symbol;Acc:MGI...
Version history
Creative Commons Attribution 4.0 International License (CC-BY-4.0)
The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .