Mouse Gene Set: REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_IKBKE
For the Human gene set with the same name, see REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_IKBKE
Standard name
REACTOME_ACTIVATION_OF_IRF3_IRF7_MEDIATED_BY_TBK1_IKK_IKBKE
Systematic name
MM15644
Brief description
Activation of IRF3, IRF7 mediated by TBK1, IKK? (IKBKE)
Full description or abstract
Collection
M2: Curated CP: Canonical Pathways CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-MMU-936964
Related gene sets
External links
https://www.reactome.org/content/detail/R-MMU-936964
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Reactome
Source platform or identifier namespace
Mouse_Ensembl_Gene_ID
Dataset references
Download gene set
format: grp | gmt | xml | json | TSV metadata
Compute overlaps ?
(show collections to investigate for overlap with this gene set)
Compendia expression profiles ?
NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds )
Mouse Transcriptomic BodyMap compendium
Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query
Further investigate
these 19 genes
Show members
(show 19 source identifiers mapped to 19 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ENSMUSG000000031 84
54131
Irf3
interferon regulatory factor 3 [S...
ENSMUSG000000083 48
22190
Ubc
ubiquitin C [Source:MGI Symbol;Ac...
ENSMUSG000000195 05
22187
Ubb
ubiquitin B [Source:MGI Symbol;Ac...
ENSMUSG000000201 15
56480
Tbk1
TANK-binding kinase 1 [Source:MGI...
ENSMUSG000000204 60
78294
Rps27a
ribosomal protein S27A [Source:MG...
ENSMUSG000000212 77
22031
Traf3
TNF receptor-associated factor 3 ...
ENSMUSG000000254 98
54123
Irf7
interferon regulatory factor 7 [S...
ENSMUSG000000257 79
17087
Ly96
lymphocyte antigen 96 [Source:MGI...
ENSMUSG000000266 72
71648
Optn
optineurin [Source:MGI Symbol;Acc...
ENSMUSG000000390 05
21898
Tlr4
toll-like receptor 4 [Source:MGI ...
ENSMUSG000000423 49
56489
Ikbke
inhibitor of kappaB kinase epsilo...
ENSMUSG000000437 33
19247
Ptpn11
protein tyrosine phosphatase, non...
ENSMUSG000000471 23
106759
Ticam1
TIR domain containing adaptor mol...
ENSMUSG000000501 32
237868
Sarm1
sterile alpha and HEAT/Armadillo ...
ENSMUSG000000514 39
12475
Cd14
CD14 antigen [Source:MGI Symbol;A...
ENSMUSG000000561 30
225471
Ticam2
TIR domain containing adaptor mol...
ENSMUSG000000642 89
21353
Tank
TRAF family member-associated Nf-...
ENSMUSG000000682 40
666586
Uba52rt
ubiquitin A-52 residue ribosomal ...
ENSMUSG000000901 37
22186
Uba52
ubiquitin A-52 residue ribosomal ...
Version history
2026.1.Mm: Updated to Reactome 95
Creative Commons Attribution 4.0 International License (CC-BY-4.0)
The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .