Mouse Gene Set: REACTOME_PYROPTOSIS
For the Human gene set with the same name, see REACTOME_PYROPTOSIS
Standard name
REACTOME_PYROPTOSIS
Systematic name
MM15212
Brief description
Pyroptosis
Full description or abstract
Collection
M2: Curated CP: Canonical Pathways CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-MMU-5620971
Related gene sets
External links
https://www.reactome.org/content/detail/R-MMU-5620971
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Reactome
Source platform or identifier namespace
Mouse_Ensembl_Gene_ID
Dataset references
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Advanced query
Further investigate
these 22 genes
Show members
(show 22 source identifiers mapped to 22 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ENSMUSG000000038 73
12028
Bax
BCL2-associated X protein [Source...
ENSMUSG000000048 43
68942
Chmp2b
charged multivesicular body prote...
ENSMUSG000000154 37
14939
Gzmb
granzyme B [Source:MGI Symbol;Acc...
ENSMUSG000000201 25
50701
Elane
elastase, neutrophil expressed [S...
ENSMUSG000000225 75
69146
Gsdmd
gasdermin D [Source:MGI Symbol;Ac...
ENSMUSG000000253 71
208092
Chmp6
charged multivesicular body prote...
ENSMUSG000000258 88
12362
Casp1
caspase 1 [Source:MGI Symbol;Acc:...
ENSMUSG000000273 98
16176
Il1b
interleukin 1 beta [Source:MGI Sy...
ENSMUSG000000273 99
16175
Il1a
interleukin 1 alpha [Source:MGI S...
ENSMUSG000000275 36
66371
Chmp4c
charged multivesicular body prote...
ENSMUSG000000298 21
54722
Gsdme
gasdermin E [Source:MGI Symbol;Ac...
ENSMUSG000000316 28
12367
Casp3
caspase 3 [Source:MGI Symbol;Acc:...
ENSMUSG000000335 38
12363
Casp4
caspase 4, apoptosis-related cyst...
ENSMUSG000000339 16
68953
Chmp2a
charged multivesicular body prote...
ENSMUSG000000341 90
105513
Chmp7
charged multivesicular body prote...
ENSMUSG000000384 67
75608
Chmp4b
charged multivesicular body prote...
ENSMUSG000000392 17
16173
Il18
interleukin 18 [Source:MGI Symbol...
ENSMUSG000000531 19
66700
Chmp3
charged multivesicular body prote...
ENSMUSG000000577 89
12018
Bak1
BCL2-antagonist/killer 1 [Source:...
ENSMUSG000000589 27
672195
Gm10053
predicted gene 10053 [Source:MGI ...
ENSMUSG000000636 94
13063
Cycs
cytochrome c, somatic [Source:MGI...
ENSMUSG000000665 51
15289
Hmgb1
high mobility group box 1 [Source...
Version history
2026.1.Mm: Updated to Reactome 95
Creative Commons Attribution 4.0 International License (CC-BY-4.0)
The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .