Mouse Gene Set: REACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING
For the Human gene set with the same name, see REACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING
Standard name
REACTOME_TNFR1_INDUCED_PROAPOPTOTIC_SIGNALING
Systematic name
MM15177
Brief description
TNFR1-induced proapoptotic signaling
Full description or abstract
Collection
M2: Curated CP: Canonical Pathways CP:REACTOME: Reactome Pathways
Source publication
Exact source
R-MMU-5357786
Related gene sets
External links
https://www.reactome.org/content/detail/R-MMU-5357786
Filtered by similarity ?
Source species
Mus musculus
Contributed by
Reactome
Source platform or identifier namespace
Mouse_Ensembl_Gene_ID
Dataset references
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Further investigate
these 23 genes
Show members
(show 23 source identifiers mapped to 23 genes)
Source Id
NCBI (Entrez) Gene Id
Gene Symbol
Gene Description
ENSMUSG000000198 50
21929
Tnfaip3
tumor necrosis factor, alpha-ind...
ENSMUSG000000201 15
56480
Tbk1
TANK-binding kinase 1 [Source:MG...
ENSMUSG000000214 08
19766
Ripk1
receptor (TNFRSF)-interacting se...
ENSMUSG000000225 52
106025
Sharpin
SHANK-associated RH domain inter...
ENSMUSG000000244 01
21926
Tnf
tumor necrosis factor [Source:MG...
ENSMUSG000000258 60
11798
Xiap
X-linked inhibitor of apoptosis ...
ENSMUSG000000269 42
22030
Traf2
TNF receptor-associated factor 2...
ENSMUSG000000274 66
24105
Rbck1
RanBP-type and C3HC4-type zinc f...
ENSMUSG000000290 60
76580
Mib2
mindbomb E3 ubiquitin protein li...
ENSMUSG000000303 41
21937
Tnfrsf1a
tumor necrosis factor receptor s...
ENSMUSG000000310 77
14082
Fadd
Fas associated via death domain ...
ENSMUSG000000318 87
71609
Tradd
TNFRSF1A-associated via death do...
ENSMUSG000000320 00
11796
Birc3
baculoviral IAP repeat-containin...
ENSMUSG000000320 10
53376
Usp2
ubiquitin specific peptidase 2 [...
ENSMUSG000000326 12
22258
Usp4
ubiquitin specific peptidase 4 (...
ENSMUSG000000367 12
74256
Cyld
CYLD lysine 63 deubiquitinase [S...
ENSMUSG000000384 95
229603
Otud7b
OTU domain containing 7B [Source...
ENSMUSG000000423 49
56489
Ikbke
inhibitor of kappaB kinase epsil...
ENSMUSG000000434 15
71198
Otud1
OTU domain containing 1 [Source:...
ENSMUSG000000470 30
263876
Spata2
spermatogenesis associated 2 [So...
ENSMUSG000000470 98
268749
Rnf31
ring finger protein 31 [Source:M...
ENSMUSG000000534 83
30941
Usp21
ubiquitin specific peptidase 21 ...
ENSMUSG000000573 67
11797
Birc2
baculoviral IAP repeat-containin...
Version history
2026.1.Mm: Updated to Reactome 95
Creative Commons Attribution 4.0 International License (CC-BY-4.0)
The contents of this gene set are protected by copyright (c) 2004-2026 Broad Institute, Inc., Massachusetts Institute of Technology,
and Regents of the University of California, subject to the terms and conditions of the
Creative Commons Attribution 4.0 International License .
See the full MSigDB license terms here .