Mouse Gene Set: ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_DN


Standard name ZEMEK_IMMUNE_CHECKPOINT_BLOCKADE_OVARIAN_CANCER_RENCA_DN
Systematic name MM459
Brief description The authors compared the cellular composition and gene expression profiles of responsive and nonresponsive tumors from BALB/cArc, BALB/cJAusb, and C57BL6/J mice before immune checkpoint blockade (ICB) and validated the findings in cohorts of patients with cancer treated with ICB antibodies.
Full description or abstract Experiments were performed using Renca renal cell carcinoma cell lines.
Collection M2: Curated
      CGP: Chemical and Genetic Perturbations
Source publication Pubmed 31316010   Authors: Zemek RM,De Jong E,Chin WL,Schuster IS,Fear VS,Casey TH,Forbes C,Dart SJ,Leslie C,Zaitouny A,Small M,Boon L,Forrest ARR,Muiri DO,Degli-Esposti MA,Millward MJ,Nowak AK,Lassmann T,Bosco A,Lake RA,Lesterhuis WJ
Exact source Data file S1. Renca
Related gene sets (show 2 additional gene sets from the source publication)
External links https://www.ncbi.nlm.nih.gov/pubmed/31316010
Filtered by similarity ?
Source species Mus musculus
Contributed by Mouse Genome Informatics (MGI) (The Jackson Laboratory (JAX))
Source platform or
identifier namespace		 MOUSE_GENE_SYMBOL
Dataset references  
Download gene set format: grp | gmt | xml | json | TSV metadata
Compute overlaps ? (show collections to investigate for overlap with this gene set)
Compendia expression profiles ? NG-CHM interactive heatmaps
(Please note that clustering takes a few seconds)
Mouse Transcriptomic BodyMap compendium

Legacy heatmaps (PNG)
Mouse Transcriptomic BodyMap compendium
Advanced query Further investigate these 8 genes
Show members (show 8 source identifiers mapped to 8 genes)
Version history 2022.1.Mm: First Introduced.

See MSigDB license terms here. Please note that certain gene sets have special access terms.