Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | NGT |
| GeneSet | C2.symbols.gmt#HTERT_DOWN |
| Enrichment Score (ES) | 0.31253758 |
| Normalized Enrichment Score (NES) | 1.2526144 |
| Nominal p-value | 0.13800906 |
| FDR q-value | 1.0 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RIG | RIG StanfordSource, GeneCards | regulated in glioma | 52 | 0.499 | 0.0514 | Yes |
| 2 | ATP5O | ATP5O StanfordSource, GeneCards | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 217 | 0.392 | 0.0836 | Yes |
| 3 | GSTO1 | GSTO1 StanfordSource, GeneCards | glutathione S-transferase omega 1 | 249 | 0.384 | 0.1237 | Yes |
| 4 | NID2 | NID2 StanfordSource, GeneCards | nidogen 2 (osteonidogen) | 274 | 0.376 | 0.1635 | Yes |
| 5 | DUSP6 | DUSP6 StanfordSource, GeneCards | dual specificity phosphatase 6 | 674 | 0.304 | 0.1703 | Yes |
| 6 | RAB11A | RAB11A StanfordSource, GeneCards | RAB11A, member RAS oncogene family | 1013 | 0.271 | 0.1776 | Yes |
| 7 | CCNG1 | CCNG1 StanfordSource, GeneCards | cyclin G1 | 1135 | 0.261 | 0.1982 | Yes |
| 8 | ACLY | ACLY StanfordSource, GeneCards | ATP citrate lyase | 1336 | 0.247 | 0.2119 | Yes |
| 9 | EHHADH | EHHADH StanfordSource, GeneCards | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 1338 | 0.246 | 0.2389 | Yes |
| 10 | TNFSF10 | TNFSF10 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 10 | 1762 | 0.217 | 0.2345 | Yes |
| 11 | TNFSF9 | TNFSF9 StanfordSource, GeneCards | tumor necrosis factor (ligand) superfamily, member 9 | 1800 | 0.215 | 0.2557 | Yes |
| 12 | TCF4 | TCF4 StanfordSource, GeneCards | transcription factor 4 | 1899 | 0.209 | 0.2722 | Yes |
| 13 | TST | TST StanfordSource, GeneCards | thiosulfate sulfurtransferase (rhodanese) | 2422 | 0.183 | 0.2574 | Yes |
| 14 | DNA2L | DNA2L StanfordSource, GeneCards | DNA2 DNA replication helicase 2-like (yeast) | 2733 | 0.167 | 0.2551 | Yes |
| 15 | PGF | PGF StanfordSource, GeneCards | placental growth factor, vascular endothelial growth factor-related protein | 2939 | 0.159 | 0.2590 | Yes |
| 16 | CALML3 | CALML3 StanfordSource, GeneCards | calmodulin-like 3 | 3020 | 0.156 | 0.2707 | Yes |
| 17 | FAH | FAH StanfordSource, GeneCards | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 3037 | 0.155 | 0.2867 | Yes |
| 18 | AKT1 | AKT1 StanfordSource, GeneCards | v-akt murine thymoma viral oncogene homolog 1 | 3210 | 0.148 | 0.2915 | Yes |
| 19 | TRADD | TRADD StanfordSource, GeneCards | TNFRSF1A-associated via death domain | 3471 | 0.138 | 0.2894 | Yes |
| 20 | PML | PML StanfordSource, GeneCards | promyelocytic leukemia | 3647 | 0.131 | 0.2920 | Yes |
| 21 | IDI1 | IDI1 StanfordSource, GeneCards | isopentenyl-diphosphate delta isomerase | 3684 | 0.129 | 0.3038 | Yes |
| 22 | AKR1C3 | AKR1C3 StanfordSource, GeneCards | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 3942 | 0.120 | 0.2999 | Yes |
| 23 | SRD5A1 | SRD5A1 StanfordSource, GeneCards | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | 3951 | 0.120 | 0.3125 | Yes |
| 24 | AHCY | AHCY StanfordSource, GeneCards | S-adenosylhomocysteine hydrolase | 4150 | 0.113 | 0.3118 | No |
| 25 | KYNU | KYNU StanfordSource, GeneCards | kynureninase (L-kynurenine hydrolase) | 4814 | 0.092 | 0.2776 | No |
| 26 | HEAB | HEAB StanfordSource, GeneCards | ATP/GTP-binding protein | 4977 | 0.087 | 0.2764 | No |
| 27 | ALDH3A2 | ALDH3A2 StanfordSource, GeneCards | aldehyde dehydrogenase 3 family, member A2 | 5369 | 0.075 | 0.2585 | No |
| 28 | VAV2 | VAV2 StanfordSource, GeneCards | vav 2 oncogene | 5900 | 0.059 | 0.2297 | No |
| 29 | PON2 | PON2 StanfordSource, GeneCards | paraoxonase 2 | 6041 | 0.054 | 0.2263 | No |
| 30 | VSNL1 | VSNL1 StanfordSource, GeneCards | visinin-like 1 | 6089 | 0.053 | 0.2289 | No |
| 31 | APEG1 | APEG1 StanfordSource, GeneCards | aortic preferentially expressed protein 1 | 6141 | 0.051 | 0.2312 | No |
| 32 | CD47 | CD47 StanfordSource, GeneCards | CD47 antigen (Rh-related antigen, integrin-associated signal transducer) | 6153 | 0.051 | 0.2360 | No |
| 33 | IL1RN | IL1RN StanfordSource, GeneCards | interleukin 1 receptor antagonist | 6221 | 0.049 | 0.2370 | No |
| 34 | PCNA | PCNA StanfordSource, GeneCards | proliferating cell nuclear antigen | 6636 | 0.038 | 0.2135 | No |
| 35 | TUBB4 | TUBB4 StanfordSource, GeneCards | tubulin, beta, 4 | 6690 | 0.036 | 0.2140 | No |
| 36 | ANXA4 | ANXA4 StanfordSource, GeneCards | annexin A4 | 7114 | 0.024 | 0.1885 | No |
| 37 | PTPNS1 | PTPNS1 StanfordSource, GeneCards | protein tyrosine phosphatase, non-receptor type substrate 1 | 7527 | 0.013 | 0.1625 | No |
| 38 | ASAH1 | ASAH1 StanfordSource, GeneCards | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | 7530 | 0.013 | 0.1638 | No |
| 39 | GM2A | GM2A StanfordSource, GeneCards | GM2 ganglioside activator protein | 7811 | 0.005 | 0.1456 | No |
| 40 | NME4 | NME4 StanfordSource, GeneCards | non-metastatic cells 4, protein expressed in | 7998 | -0.000 | 0.1332 | No |
| 41 | ARHGDIB | ARHGDIB StanfordSource, GeneCards | Rho GDP dissociation inhibitor (GDI) beta | 9027 | -0.030 | 0.0680 | No |
| 42 | TAGLN | TAGLN StanfordSource, GeneCards | transgelin | 9427 | -0.042 | 0.0460 | No |
| 43 | DHCR24 | DHCR24 StanfordSource, GeneCards | 24-dehydrocholesterol reductase | 9548 | -0.046 | 0.0431 | No |
| 44 | PCOLN3 | PCOLN3 StanfordSource, GeneCards | procollagen (type III) N-endopeptidase | 9769 | -0.053 | 0.0342 | No |
| 45 | ANKRD15 | ANKRD15 StanfordSource, GeneCards | ankyrin repeat domain 15 | 10430 | -0.076 | -0.0015 | No |
| 46 | SAA1 | SAA1 StanfordSource, GeneCards | serum amyloid A1 | 10459 | -0.077 | 0.0051 | No |
| 47 | SORD | SORD StanfordSource, GeneCards | sorbitol dehydrogenase | 10510 | -0.079 | 0.0104 | No |
| 48 | GSN | GSN StanfordSource, GeneCards | gelsolin (amyloidosis, Finnish type) | 10584 | -0.081 | 0.0144 | No |
| 49 | SERPING1 | SERPING1 StanfordSource, GeneCards | serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 10614 | -0.082 | 0.0215 | No |
| 50 | KIAA0140 | KIAA0140 StanfordSource, GeneCards | KIAA0140 gene product | 10760 | -0.087 | 0.0214 | No |
| 51 | STAT4 | STAT4 StanfordSource, GeneCards | signal transducer and activator of transcription 4 | 10956 | -0.094 | 0.0187 | No |
| 52 | POU5F1 | POU5F1 StanfordSource, GeneCards | POU domain, class 5, transcription factor 1 | 10983 | -0.095 | 0.0274 | No |
| 53 | ALDH7A1 | ALDH7A1 StanfordSource, GeneCards | aldehyde dehydrogenase 7 family, member A1 | 11086 | -0.098 | 0.0314 | No |
| 54 | A2M | A2M StanfordSource, GeneCards | alpha-2-macroglobulin | 11159 | -0.101 | 0.0377 | No |
| 55 | RAB40B | RAB40B StanfordSource, GeneCards | RAB40B, member RAS oncogene family | 11226 | -0.103 | 0.0446 | No |
| 56 | CBR1 | CBR1 StanfordSource, GeneCards | carbonyl reductase 1 | 11385 | -0.109 | 0.0460 | No |
| 57 | PAM | PAM StanfordSource, GeneCards | peptidylglycine alpha-amidating monooxygenase | 11576 | -0.116 | 0.0461 | No |
| 58 | PPP1R7 | PPP1R7 StanfordSource, GeneCards | protein phosphatase 1, regulatory subunit 7 | 11978 | -0.132 | 0.0339 | No |
| 59 | FOSB | FOSB StanfordSource, GeneCards | FBJ murine osteosarcoma viral oncogene homolog B | 12093 | -0.137 | 0.0413 | No |
| 60 | ABR | ABR StanfordSource, GeneCards | active BCR-related gene | 12254 | -0.145 | 0.0466 | No |
| 61 | PIK3R3 | PIK3R3 StanfordSource, GeneCards | phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma) | 12414 | -0.152 | 0.0526 | No |
| 62 | GAMT | GAMT StanfordSource, GeneCards | guanidinoacetate N-methyltransferase | 13107 | -0.191 | 0.0274 | No |
| 63 | XRCC5 | XRCC5 StanfordSource, GeneCards | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 13496 | -0.216 | 0.0253 | No |
| 64 | RRAGA | RRAGA StanfordSource, GeneCards | Ras-related GTP binding A | 13651 | -0.227 | 0.0399 | No |
| 65 | UNC119 | UNC119 StanfordSource, GeneCards | unc-119 homolog (C. elegans) | 13860 | -0.244 | 0.0528 | No |
| 66 | UGP2 | UGP2 StanfordSource, GeneCards | UDP-glucose pyrophosphorylase 2 | 13866 | -0.244 | 0.0793 | No |
