Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Diabetes_collapsed.gct |
| Phenotype | DMT |
| GeneSet | C2.symbols.gmt#MAP00500_Starch_and_sucrose_metabolism |
| Enrichment Score (ES) | -0.46484077 |
| Normalized Enrichment Score (NES) | -1.4876654 |
| Nominal p-value | 0.045889102 |
| FDR q-value | 1.0 |
| FWER p-Value | 0.952 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RES | CORE_ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HK2 | HK2 StanfordSource, GeneCards | hexokinase 2 | 1165 | 0.259 | -0.0066 | No |
| 2 | GAA | GAA StanfordSource, GeneCards | glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II) | 1538 | 0.231 | 0.0320 | No |
| 3 | HK3 | HK3 StanfordSource, GeneCards | hexokinase 3 (white cell) | 3343 | 0.143 | -0.0488 | No |
| 4 | UGT2B15 | UGT2B15 StanfordSource, GeneCards | UDP glycosyltransferase 2 family, polypeptide B15 | 3636 | 0.131 | -0.0322 | No |
| 5 | GUSB | GUSB StanfordSource, GeneCards | glucuronidase, beta | 3992 | 0.119 | -0.0233 | No |
| 6 | PGM1 | PGM1 StanfordSource, GeneCards | phosphoglucomutase 1 | 5131 | 0.082 | -0.0765 | No |
| 7 | GCK | GCK StanfordSource, GeneCards | glucokinase (hexokinase 4, maturity onset diabetes of the young 2) | 6745 | 0.035 | -0.1742 | No |
| 8 | GYS2 | GYS2 StanfordSource, GeneCards | glycogen synthase 2 (liver) | 8529 | -0.016 | -0.2885 | No |
| 9 | GBE1 | GBE1 StanfordSource, GeneCards | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 9332 | -0.040 | -0.3309 | No |
| 10 | HK1 | HK1 StanfordSource, GeneCards | hexokinase 1 | 11003 | -0.096 | -0.4158 | No |
| 11 | UGT2B4 | UGT2B4 StanfordSource, GeneCards | UDP glycosyltransferase 2 family, polypeptide B4 | 11127 | -0.100 | -0.3967 | No |
| 12 | PYGL | PYGL StanfordSource, GeneCards | phosphorylase, glycogen; liver (Hers disease, glycogen storage disease type VI) | 12152 | -0.140 | -0.4265 | Yes |
| 13 | AGL | AGL StanfordSource, GeneCards | amylo-1, 6-glucosidase, 4-alpha-glucanotransferase (glycogen debranching enzyme, glycogen storage disease type III) | 12197 | -0.143 | -0.3904 | Yes |
| 14 | MGAM | MGAM StanfordSource, GeneCards | maltase-glucoamylase (alpha-glucosidase) | 12849 | -0.175 | -0.3858 | Yes |
| 15 | PYGM | PYGM StanfordSource, GeneCards | phosphorylase, glycogen; muscle (McArdle syndrome, glycogen storage disease type V) | 12918 | -0.180 | -0.3411 | Yes |
| 16 | GYS1 | GYS1 StanfordSource, GeneCards | glycogen synthase 1 (muscle) | 13784 | -0.237 | -0.3338 | Yes |
| 17 | PYGB | PYGB StanfordSource, GeneCards | phosphorylase, glycogen; brain | 13830 | -0.241 | -0.2708 | Yes |
| 18 | UGP2 | UGP2 StanfordSource, GeneCards | UDP-glucose pyrophosphorylase 2 | 13866 | -0.244 | -0.2062 | Yes |
| 19 | GPI | GPI StanfordSource, GeneCards | glucose phosphate isomerase | 14378 | -0.301 | -0.1578 | Yes |
| 20 | G6PC | G6PC StanfordSource, GeneCards | glucose-6-phosphatase, catalytic (glycogen storage disease type I, von Gierke disease) | 14736 | -0.363 | -0.0821 | Yes |
| 21 | ADH6 | ADH6 StanfordSource, GeneCards | alcohol dehydrogenase 6 (class V) | 14792 | -0.377 | 0.0175 | Yes |
